Optimization of Adaptive Text Messages for Cancer Survivors (OATS II)

NCT ID: NCT05746195

Last Updated: 2024-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-03

Study Completion Date

2024-11-30

Brief Summary

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This clinical trial evaluates whether an adaptive text-message intervention is useful in helping survivors of colorectal cancers (CRC) eat more whole grain foods and less refined grain foods. Most CRC survivors don't achieve the recommended intakes of whole grains or fiber, even though there is strong evidence that a high-fiber diet rich in whole grains lowers the risk of death from CRC. Dietary interventions are a promising approach for reducing death from CRC, and text message interventions specifically are a promising tool for reaching diverse populations. This trial evaluates a text-message based dietary intervention that continuously adapts message content to be specifically tailored for the participant for increasing whole grain consumption.

Detailed Description

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PRIMARY OBJECTIVE:

I. Determine the intervention's feasibility and acceptability.

SECONDARY OBJECTIVES:

I. Estimate the effect of the intervention on the percent of grains consumed that are whole.

II. Estimate the effect of the intervention on total fiber intake (grams per day \[g/d\]).

EXPLORATORY OBJECTIVE:

I. Assess convergence of the reinforcement learning (RL) algorithm.

OUTLINE:

Patients receive nutrition education materials and then receive the adaptive text message intervention for 12 weeks on study. Patients who are food insecure also receive resources for food banks, information about meal delivery programs, and support for applying for Supplemental Nutrition Assistance Program (SNAP) benefits.

Conditions

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Colon Adenocarcinoma Colorectal Carcinoma Rectal Adenocarcinoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Text message intervention

Adaptive 12-week text message intervention using reinforcement learning to increase whole grain and reduce refined grain intake. Participants will also complete semi-structured follow-up interviews and study related questionnaires.

Group Type EXPERIMENTAL

Dietary intervention via Text Messaging

Intervention Type BEHAVIORAL

Text messages will be sent to participants cell phones using the HealthySMS platform

Survey Administration

Intervention Type OTHER

Various questionnaires evaluating participants dietary habits and use of study intervention will be administered

Nutrition Education

Intervention Type BEHAVIORAL

Participants will receive nutrition education materials

Interventions

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Dietary intervention via Text Messaging

Text messages will be sent to participants cell phones using the HealthySMS platform

Intervention Type BEHAVIORAL

Survey Administration

Various questionnaires evaluating participants dietary habits and use of study intervention will be administered

Intervention Type OTHER

Nutrition Education

Participants will receive nutrition education materials

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Age \> 18 years.
2. Subject has provided informed consent.
3. Diagnosis of colon or rectal adenocarcinoma.
4. Not on active treatment at the time of screening and not expected to receive active anticancer therapy (e.g., surgery, radiation, chemotherapy) during the study period.
5. At least 6 weeks since a major surgery and fully recovered.
6. Owns a mobile phone and is willing and able to receive and send text messages.
7. Able to speak/read English or Spanish.
8. Based on a screening survey, eat grains and =\<50% of total grains are whole grains.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Erin Van Blarigan, ScD

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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Zuckerberg San Francisco General

San Francisco, California, United States

Site Status

University of California, San Francisco

San Francisco, California, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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NCI-2023-00870

Identifier Type: REGISTRY

Identifier Source: secondary_id

R21CA263539

Identifier Type: NIH

Identifier Source: secondary_id

View Link

224523

Identifier Type: -

Identifier Source: org_study_id