Effect of Sleep Disorder on the Development of Lung Tumors

NCT ID: NCT05745506

Last Updated: 2023-02-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-28

Study Completion Date

2026-12-31

Brief Summary

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The goal of this observational study is to observe the lung tumor development in lung tumor patients with long-term sleep disorder. The main questions it aims to answer are:

* will long-term sleep disorder promote the malignancy of lung tumor
* if so, how exactly will the microenvironment of lung tumor change Participants will receive PSQI scale and MRI functional brain imaging before surgery, blood and tumor tissue will be collected during the surgery.

Researchers will set non-sleep disorder group as control group to see if lung tumor microenvironment change when long-term sleep disorder exists in lung tumor patiens.

Detailed Description

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Conditions

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Sleep Disorder, Lung Tumor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CRD

patients whose PSQI score\>5

Intervention Type OTHER

Not applicable, there is no intervention description in this study.

non-CRD

patients whose PSQI score ≦ 5

Intervention Type OTHER

Not applicable, there is no intervention description in this study.

Interventions

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Not applicable, there is no intervention description in this study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18-75 years old
* elective sublobectomy for primary lung tumor
* ASA grade I-II
* Informed consent of the patient or family

Exclusion Criteria

* Combination of serious heart, liver, kidney, central nervous system, blood system, immune system diseases or serious mental illness
* Combination of other cancers
* untreated active lung infection
* patients with preoperative neoadjuvant radiotherapy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Weifeng Yu

Role: STUDY_DIRECTOR

Department of Anesthesiology, Renji Hospital, Shanghai Jiaotong University School of Medicine

Central Contacts

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Weifeng Yu

Role: CONTACT

13901961704

Yumiao Shi

Role: CONTACT

19821850236

Other Identifiers

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IIT-2022-0160

Identifier Type: -

Identifier Source: org_study_id

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