The Long COVID-19 Wearable Device Study

NCT ID: NCT05741112

Last Updated: 2025-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100500 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-16

Study Completion Date

2025-12-01

Brief Summary

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To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can improve Long COVID-19 symptom management and post-exertional malaise.

Detailed Description

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This study will have two components:

One study group will consist of up to 100,000 individuals who own wearable devices and are willing to share their data. These participants will be randomized and will receive educational materials. The investigators will study these dynamic wearable data along with participant survey responses that focus on diagnoses, symptoms, and quality of life to improve disease characterization and understanding of differences within and between individuals.

The other group in the randomized trial will participants who do not already own a wearable device. The study will distribute wearable devices and pacing educational materials to 500 individuals who do not already own them and experience post-exertional malaise, or the worsening of symptoms following exertion.

The investigators hypothesize that access to personalized information from a wearable device will enable participants to reduce post-exertional malaise. The investigators will include up to 25% individuals whose post-exertional malaise is caused by a condition other than Long COVID-19.

Conditions

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Long COVID Postural Orthostatic Tachycardia Syndrome Dysautonomia Myalgic Encephalomyelitis Chronic Fatigue Syndrome Long Covid19

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

All participants will have a diagnosis of Long COVID-19, Chronic Fatigue Syndrome or Postural Orthostatic Tachycardia Syndrome.
Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Control: study provided wearables

Following consent and the completion of the baseline assessments the control group will receive basic education on symptom management. At the 3 month timepoint they will be prompted to order their device and receive enhanced education that will provide information on how wearable devices can be used to monitor and manage symptoms.

Group Type OTHER

Wearable device

Intervention Type DEVICE

The treatment group will receive their wearable device and the enhanced education at the start of the study. Their outcomes will be compared with the control group who will receive at 3 months.

Treatment: study provided wearables

Following consent and the completion of the baseline assessments the treatment group will be prompted to order their device and receive basic education on symptom management along with the enhanced education on wearable devices.

Group Type OTHER

Wearable device

Intervention Type DEVICE

The treatment group will receive their wearable device and the enhanced education at the start of the study. Their outcomes will be compared with the control group who will receive at 3 months.

Control: self provided wearables

Following consent and the completion of the baseline assessments the control group will receive basic education on symptom management. At the 3 month timepoint they will be receive enhanced education that will provide information on how wearable devices can be used to monitor and manage symptoms.

Group Type OTHER

Wearable device

Intervention Type DEVICE

The treatment group will receive their wearable device and the enhanced education at the start of the study. Their outcomes will be compared with the control group who will receive at 3 months.

Treatment: self provided wearables

Following consent and the completion of the baseline assessments the treatment group will receive basic education on symptom management along with the enhanced education on wearable devices.

Group Type OTHER

Wearable device

Intervention Type DEVICE

The treatment group will receive their wearable device and the enhanced education at the start of the study. Their outcomes will be compared with the control group who will receive at 3 months.

Interventions

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Wearable device

The treatment group will receive their wearable device and the enhanced education at the start of the study. Their outcomes will be compared with the control group who will receive at 3 months.

Intervention Type DEVICE

Other Intervention Names

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Educational materials

Eligibility Criteria

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Inclusion Criteria

* Is at least 18 years old.
* Has a self/and or physician diagnosis of:
* Long COVID (based on the WHO working definition),
* ME/CFS (myalgic encephalomyelitis / chronic fatigue syndrome, self-diagnosis based on IOM criteria), and/or
* POTS (Postural Orthostatic Tachycardia Syndrome).
* Is interested in tools to manage ME/CFS, POTS, and/or Long COVID symptoms.
* Owns a wearable device they are willing to use for this study or does not own a device and agrees to utilize a study-provided one.
* Agrees to wear the device throughout the study period, share the data with the study, and sync data at least weekly.
* Has access to a smartphone or tablet to enable syncing wearable data and viewing device feedback.
* Agrees to disclose involvement in other ME/CFS, POTS, and/or Long COVID interventions such as medical treatment, self-management, and other interventional studies.
* Agrees to complete at least 75% of the study surveys.

Exclusion Criteria

* As long as they meet inclusion there is no exclusion
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Scripps Translational Science Institute

OTHER

Sponsor Role lead

Responsible Party

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Julia Moore Vogel

Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Scripps Research

La Jolla, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Andrea Goosen

Role: CONTACT

0000000000

Romina Foster-Bonds

Role: CONTACT

Facility Contacts

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Andrea Goosen

Role: primary

Other Identifiers

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LCWS 001

Identifier Type: -

Identifier Source: org_study_id

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