Intubation Conditions After RSI Using Rocuronium with Ephedrine Pretreatment
NCT ID: NCT05725031
Last Updated: 2024-10-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
75 participants
INTERVENTIONAL
2023-04-01
2024-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
SINGLE
Study Groups
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ER6
to receive rocuronium 0.6 mg/kg with ephedrine pretreatment
Ephedrine
70 μg/kg as pretreatment
Rocuronium 0.6
0.6 mg/kg
ER8
to receive rocuronium 0.8 mg/kg with ephedrine pretreatment
Ephedrine
70 μg/kg as pretreatment
Rocuronium 0.8
0.8 mg/kg
R12
to receive rocuronium 1.2 mg/kg with no pretreatment
Rocuronium 1.2
1.2 mg/kg
Interventions
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Ephedrine
70 μg/kg as pretreatment
Rocuronium 0.6
0.6 mg/kg
Rocuronium 0.8
0.8 mg/kg
Rocuronium 1.2
1.2 mg/kg
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* On drugs that interact with the neuromuscular junction or ephedrine
* Cardiovascular disease: hypertension or ischemic heart disease
* Increased risk of pulmonary aspiration:
* GERD
* Pregnancy
* Anticipated airway difficulties:
* Mallampati grade III or IV
* Obesity (BMI ≥30 kg/m2),
* Hypersensitivity to any of the study drugs
18 Years
60 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Amal Ahmed Eldemohi
Resident of Anesthesiology
Locations
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Ain Shams University Hospitals
Cairo, , Egypt
Countries
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Other Identifiers
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Eph-Roc
Identifier Type: -
Identifier Source: org_study_id
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