Dental Care and Initiation of Anti-osteoporotic Therapy

NCT ID: NCT05719818

Last Updated: 2023-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

338 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-03

Study Completion Date

2022-01-04

Brief Summary

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The initiation of bisphosphonate therapy for osteoporosis requires an assessment of the oral status to prevent the risk of osteonecrosis of the jaw. This recommendation is sometimes a hindrance to the initiation of treatment or may be responsible for a delay in treatment or even the failure to initiate treatment. However, in the case of a severe osteoporotic fracture (femoral or humeral neck fracture, vertebral fracture or pelvic fracture), treatment must be rapid because of the major risk of refracture in the short term (multiplied by 5 in the 2 years following the fracture).

In the rheumatology department of the Nice University Hospital, the investigator team take care of patients with osteoporotic fractures either directly in hospital or referred by the orthopedics department as part of a care program. For these patients, the team perform an etiological assessment, bone densitometry and evaluation of the oral status with dental panoramic and tele-expertise to determine if there is an indication to perform surgical care before starting the treatment.

Therefore, the investigator aimed to describe the number of patients requiring dental surgery befor the initiation of bisphosphonate or denosumab treatment before to introduce treatment for osteoporosis

Detailed Description

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Conditions

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Dental Condition Osteoporosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Treatment initiation

patients with a satisfactory oral assessment authorizing the immediate prescription of treatment.

biphosphonates

Intervention Type DRUG

Initiation of bisphosphonate therapy

Surgical dental care

patients requiring surgical dental care before treatment initaition.

Dental care

Intervention Type PROCEDURE

Surgical dental care

Interventions

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biphosphonates

Initiation of bisphosphonate therapy

Intervention Type DRUG

Dental care

Surgical dental care

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* osteoporotic fracture requiring treatment with bisphosphonate or denosumab

Exclusion Criteria

* osteoporotic fracture requiring teriparatide treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nice

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de NICE

Nice, CHUN, France

Site Status

Countries

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France

Other Identifiers

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22Rhumato04

Identifier Type: -

Identifier Source: org_study_id

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