Exploring Radiotherapy of Temporomandibular Joint Arthritis

NCT ID: NCT05716737

Last Updated: 2025-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-07

Study Completion Date

2027-07-07

Brief Summary

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With this pilot study, the acute side effects and potential pain relieve after radiotherapy (RT) of the temporomandibular joint (TMJ) are prospectively recorded.

For this purpose, the symptoms of the jaw joint arthrosis/arthritis are recorded using a symptom-oriented questionnaire and the numeric rating scale for pain assessment.

Furthermore, it is examined whether the irradiation is feasible.

Detailed Description

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Conditions

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Arthritis of Temporomandibular Joint

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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TMJ RT

Patients receiving irradiation to the TMJ

Group Type EXPERIMENTAL

Irradiation

Intervention Type RADIATION

3 Gy in 6 fractions to the TMJ, every other day, LINAC based

Interventions

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Irradiation

3 Gy in 6 fractions to the TMJ, every other day, LINAC based

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* TMJ arthritis
* diagnosed by a surgeon for oral and maxillofacial surgery or a dentist

Exclusion Criteria

* Previous irradiation in the TMJ area
* Age below 50 years
Minimum Eligible Age

50 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Vienna

OTHER

Sponsor Role lead

Responsible Party

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Cora Waldstein

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Medical University of Vienna

Vienna, , Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Cora Waldstein, MD

Role: CONTACT

004314040026920

Matthias Moll, MD

Role: CONTACT

004314040026920

Facility Contacts

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Cora Waldstein, MD

Role: primary

004314040026920

Matthias Moll, MD

Role: backup

004314040026920

Other Identifiers

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TMJRT1107/2023

Identifier Type: -

Identifier Source: org_study_id

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