Application Study of Infusing Irritant Medications Through Midline Catheter Based on Real World Study

NCT ID: NCT05710835

Last Updated: 2023-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2024-06-30

Brief Summary

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The goal of this observational study is to learn about the effect on midline catheter outcomes when infusing irritant medications through midline catheter. The main questions it aims to answer are:Identify the current situation of infusing irritant medications through midline catheter;Explore the effect on midline catheter outcomes when infusing irritant medications through midline catheter;Identify specific medications that affect catheter outcomes.

Detailed Description

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First, the patients were divided into two groups according to whether irritant medications were infused or not,then observed the rate of complications between the two groups.Second, grouped according to the irritant medications, Identify specific medications that affect catheter outcomes through statistical analysis.

Conditions

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Catheter Complications

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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irritant medications group

Patients who used midline catheter to infuse irritant medications.

No interventions assigned to this group

nonirritant medications group

Patients who used midline catheter to infuse nonirritant medications.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age ≥14 years old
* Patients who had a midline catheter

Exclusion Criteria

* Patients who received vesicant medications through the midline catheter
* Patients who had both a midline catheter and a central vascular access device
Minimum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sir Run Run Shaw Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhao Linfang

assitant nursing director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Linfang Zhao

Role: PRINCIPAL_INVESTIGATOR

Sir Run Run Shaw Hospital

Locations

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Linfang Zhao

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Linfang Zhao

Role: CONTACT

13588819123

Xiuzhu Cao

Role: CONTACT

13588477316

Facility Contacts

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Linfang Zhao

Role: primary

13588819123

Xiuzhu Cao

Role: backup

13588477316

References

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Reference Type BACKGROUND
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PMID: 33049486 (View on PubMed)

Anderson J,Greenwell A,Louderback J,et al.Comparison of Outcomes of Extended Dwell/Midline Peripheral Intravenous Catheters and Peripherally Inserted Central Catheters in Children[J].Journal of Vascular Access,2016,21(3): 158-164.

Reference Type BACKGROUND

Knottnerus JA, Tugwell P. Real world research. J Clin Epidemiol. 2010 Oct;63(10):1051-2. doi: 10.1016/j.jclinepi.2010.08.001. No abstract available.

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PMID: 20728043 (View on PubMed)

Mermel LA, Parenteau S, Tow SM. The risk of midline catheterization in hospitalized patients. A prospective study. Ann Intern Med. 1995 Dec 1;123(11):841-4. doi: 10.7326/0003-4819-123-11-199512010-00005.

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Alexandrou E,Ramjan LM,Spencer T,et al.The use of midline catheters in the adult acute care setting-clinical implications and recommendations for practice[J]. Journal of the Association for Vascular Access,2011,16(1): 35-41.

Reference Type BACKGROUND

Marsh N, Webster J, Larson E, Cooke M, Mihala G, Rickard CM. Observational Study of Peripheral Intravenous Catheter Outcomes in Adult Hospitalized Patients: A Multivariable Analysis of Peripheral Intravenous Catheter Failure. J Hosp Med. 2018 Feb 1;13(2):83-89. doi: 10.12788/jhm.2867. Epub 2017 Oct 18.

Reference Type BACKGROUND
PMID: 29073316 (View on PubMed)

Anderson NR. Midline catheters: the middle ground of intravenous therapy administration. J Infus Nurs. 2004 Sep-Oct;27(5):313-21. doi: 10.1097/00129804-200409000-00005.

Reference Type BACKGROUND
PMID: 15385895 (View on PubMed)

O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S; Healthcare Infection Control Practices Advisory Committee. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control. 2011 May;39(4 Suppl 1):S1-34. doi: 10.1016/j.ajic.2011.01.003. No abstract available.

Reference Type BACKGROUND
PMID: 21511081 (View on PubMed)

Mushtaq A, Navalkele B, Kaur M, Krishna A, Saleem A, Rana N, Gera S, Chandramohan S, Surapaneni M, Chopra T. Comparison of complications in midlines versus central venous catheters: Are midlines safer than central venous lines? Am J Infect Control. 2018 Jul;46(7):788-792. doi: 10.1016/j.ajic.2018.01.006. Epub 2018 Mar 7.

Reference Type BACKGROUND
PMID: 29525366 (View on PubMed)

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Reference Type BACKGROUND
PMID: 31047692 (View on PubMed)

Sharp R, Esterman A, McCutcheon H, Hearse N, Cummings M. The safety and efficacy of midlines compared to peripherally inserted central catheters for adult cystic fibrosis patients: a retrospective, observational study. Int J Nurs Stud. 2014 May;51(5):694-702. doi: 10.1016/j.ijnurstu.2013.09.002. Epub 2013 Sep 14.

Reference Type BACKGROUND
PMID: 24103730 (View on PubMed)

Lisova K, Hromadkova J, Pavelkova K, Zauska V, Havlin J, Charvat J. The incidence of symptomatic upper limb venous thrombosis associated with midline catheter: Prospective observation. J Vasc Access. 2018 Sep;19(5):492-495. doi: 10.1177/1129729818761276. Epub 2018 Mar 16.

Reference Type BACKGROUND
PMID: 29546782 (View on PubMed)

Dickson HG, Flynn O, West D, Alexandrou E, Mifflin N, Malone M. A Cluster of Failures of Midline Catheters in a Hospital in the Home Program: A Retrospective Analysis. J Infus Nurs. 2019 Jul/Aug;42(4):203-208. doi: 10.1097/NAN.0000000000000330.

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PMID: 31283663 (View on PubMed)

Cawcutt KA, Hankins RJ, Micheels TA, Rupp ME. Optimizing vascular-access device decision-making in the era of midline catheters. Infect Control Hosp Epidemiol. 2019 Jun;40(6):674-680. doi: 10.1017/ice.2019.49. Epub 2019 Mar 29.

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Nielsen EB, Antonsen L, Mensel C, Milandt N, Dalgaard LS, Illum BS, Arildsen H, Juhl-Olsen P. The efficacy of midline catheters-a prospective, randomized, active-controlled study. Int J Infect Dis. 2021 Jan;102:220-225. doi: 10.1016/j.ijid.2020.10.053. Epub 2020 Oct 28.

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PMID: 33129962 (View on PubMed)

Elli S, Pittiruti M, Pigozzo V, Cannizzo L, Giannini L, Siligato A, Rondelli E, Foti G, Lucchini A. Ultrasound-guided tip location of midline catheters. J Vasc Access. 2020 Sep;21(5):764-768. doi: 10.1177/1129729820907250. Epub 2020 Feb 28.

Reference Type BACKGROUND
PMID: 32106761 (View on PubMed)

Caparas JV, Hu JP. Safe administration of vancomycin through a novel midline catheter: a randomized, prospective clinical trial. J Vasc Access. 2014 Jul-Aug;15(4):251-6. doi: 10.5301/jva.5000220. Epub 2014 Apr 8.

Reference Type BACKGROUND
PMID: 24811603 (View on PubMed)

Other Identifiers

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IVTEAM202301

Identifier Type: -

Identifier Source: org_study_id

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