Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
15 participants
INTERVENTIONAL
2021-12-01
2022-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Conventional therapy with RF microneedle
Half face Oral tranexamic acid combined with triple combination cream with RF microneedle
RF Microneedle
Pulsed-type RF device in bipolar mode with 25 non-insulated microneedles every 2 weeks for 6 month
Combination cream
5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone twice daily for 2 months
Conventional therapy
Half face Oral tranexamic acid combined with triple combination cream
Combination cream
5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone twice daily for 2 months
Interventions
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RF Microneedle
Pulsed-type RF device in bipolar mode with 25 non-insulated microneedles every 2 weeks for 6 month
Combination cream
5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone twice daily for 2 months
Eligibility Criteria
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Inclusion Criteria
* Melasma clinically diagnosed by three dermatologists
Exclusion Criteria
* Use of topical depigmenting agents in three months prior to the study
* Pregnant or lactating
20 Years
FEMALE
No
Sponsors
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Ajou University School of Medicine
OTHER
Responsible Party
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Jin Cheol Kim
Principal Investigator, Clinical Fellow
Locations
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Ajou University Hospital
Suwon, , South Korea
Countries
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References
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Han HJ, Kim JC, Park YJ, Kang HY. Targeting the dermis for melasma maintenance treatment. Sci Rep. 2024 Jan 10;14(1):949. doi: 10.1038/s41598-023-51133-w.
Other Identifiers
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AJOUIRB-INT-2021-133
Identifier Type: -
Identifier Source: org_study_id
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