Prognostic Value of Some Biochemical Markers in Breast Cancer

NCT ID: NCT05699577

Last Updated: 2023-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-28

Study Completion Date

2023-12-31

Brief Summary

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breast cancer is the most common type of cancer in women and first cause of cancer death among them. in Egypt it constitutes 33% of female cancer cases and more than22000 new cases diagnosed each year. there are many prognostic factors for breast cancer as Tumer size, axillary lymph node status, hormonal receptor status, and tumer markers as Ca15-3 and interferon gamma.

Detailed Description

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Conditions

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Breast Cancer Female

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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metastatic breast cancer

serum sample for ELIZA

Intervention Type DIAGNOSTIC_TEST

ELIZA for Ca15-3 and interferon gamma

non metastatic breast cancer

serum sample for ELIZA

Intervention Type DIAGNOSTIC_TEST

ELIZA for Ca15-3 and interferon gamma

Interventions

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serum sample for ELIZA

ELIZA for Ca15-3 and interferon gamma

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* female patients aged more than or equal 18 year diagnosed with breast cancer
* metastatic and non-metastatic cancer premenopausal and postmenopausal female positive and negative hormonal receptors and HER2 receptor taking any systemic treatment taking radiotherapy or not

Exclusion Criteria

* female patients less than 18 years patients having comorbid disease. patients with double malignancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Amany Fathy Abdelrasoul

demonestrator at medical biochemistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag University Hospital

Sohag, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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amany f abd alrasol, demonstrator

Role: CONTACT

01065211221

muhammed a abd el moety, professor

Role: CONTACT

Facility Contacts

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magdy m amin, professor

Role: primary

References

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Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.

Reference Type BACKGROUND
PMID: 33538338 (View on PubMed)

Uygur MM, Gumus M. The utility of serum tumor markers CEA and CA 15-3 for breast cancer prognosis and their association with clinicopathological parameters. Cancer Treat Res Commun. 2021;28:100402. doi: 10.1016/j.ctarc.2021.100402. Epub 2021 May 24.

Reference Type BACKGROUND
PMID: 34082362 (View on PubMed)

Jorgovanovic D, Song M, Wang L, Zhang Y. Roles of IFN-gamma in tumor progression and regression: a review. Biomark Res. 2020 Sep 29;8:49. doi: 10.1186/s40364-020-00228-x. eCollection 2020.

Reference Type BACKGROUND
PMID: 33005420 (View on PubMed)

Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC. Structure of the IFNgamma receptor complex guides design of biased agonists. Nature. 2019 Mar;567(7746):56-60. doi: 10.1038/s41586-019-0988-7. Epub 2019 Feb 27.

Reference Type BACKGROUND
PMID: 30814731 (View on PubMed)

Other Identifiers

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Soh-Med-23-01-07

Identifier Type: -

Identifier Source: org_study_id

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