Trial Outcomes & Findings for PMCF Study on the Safety, Performance and Clinical Benefits Data of the Quattro X Broadband (NCT NCT05690776)

NCT ID: NCT05690776

Last Updated: 2025-09-10

Results Overview

The investigator will clinically evaluate at 1 year follow-up visit if soft tissue to bone healing has occurred by the absence of device-related revisions and re-tears that were not previously reported. The following question will be asked to the investigator: "Did soft tissue to bone healing occur"? If "yes" is answered, then the soft tissue to bone healing is successful, if "no" is answered, then the soft tissue to bone healing is considered unsuccessful.

Recruitment status

COMPLETED

Target enrollment

106 participants

Primary outcome timeframe

From operation to study completion, 0-1 year

Results posted on

2025-09-10

Participant Flow

Participant milestones

Participant milestones
Measure
Patients Who Received the Quattro X BroadBand
No specific interventions will be administered.
Overall Study
STARTED
106
Overall Study
COMPLETED
106
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Age, Customized
Age at surgery
61.6 Years
STANDARD_DEVIATION 8.6 • n=106 Participants
Sex: Female, Male
Female
40 Participants
n=106 Participants
Sex: Female, Male
Male
66 Participants
n=106 Participants
BMI
26.0 kg/m2
STANDARD_DEVIATION 3.3 • n=106 Participants
Symptom Duration
349.7 days
STANDARD_DEVIATION 372.8 • n=106 Participants
Weight
75.2 kg
STANDARD_DEVIATION 11.7 • n=106 Participants
Height
169.9 cm
STANDARD_DEVIATION 8.9 • n=106 Participants
Operated Side
Left
34 Participants
n=106 Participants
Operated Side
Right
72 Participants
n=106 Participants
Patient Employment Before Surgery
Full Time
50 Participants
n=106 Participants
Patient Employment Before Surgery
Parti Time
6 Participants
n=106 Participants
Patient Employment Before Surgery
Retired
47 Participants
n=106 Participants
Patient Employment Before Surgery
Not Employed
3 Participants
n=106 Participants
Dominant Shoulder
Left
7 Participants
n=106 Participants
Dominant Shoulder
Right
99 Participants
n=106 Participants
Current Tobacco Use
None
97 Participants
n=106 Participants
Current Tobacco Use
Less than one pack per day
9 Participants
n=106 Participants
Current Alcohol Use
None
91 Participants
n=106 Participants
Current Alcohol Use
Daily
1 Participants
n=106 Participants
Current Alcohol Use
Weekly
5 Participants
n=106 Participants
Current Alcohol Use
Monthly
4 Participants
n=106 Participants
Current Alcohol Use
Occasionally
5 Participants
n=106 Participants
Constant and Murley
49.9 units on a scale
STANDARD_DEVIATION 8.4 • n=50 Participants • not all patients had baseline data available
EQ5D
0.882 units on a scale
STANDARD_DEVIATION 0.119 • n=50 Participants • not all patients had baseline data available
Subjective Shoulder Value
63.3 Percentage
STANDARD_DEVIATION 9.1 • n=49 Participants • not all patients had baseline data available
Prior Ipsilateral Shoulder Infection
Yes
0 Participants
n=106 Participants
Prior Ipsilateral Shoulder Infection
No
106 Participants
n=106 Participants
Prior Contralateral Shoulder Infection
Yes
0 Participants
n=106 Participants
Prior Contralateral Shoulder Infection
No
106 Participants
n=106 Participants
Prior Shoulder Operation(s)
Contralateral Rotator Cuff Repair
3 Participants
n=106 Participants
Prior Shoulder Operation(s)
Ipsilateral Rotator Cuff Repair
1 Participants
n=106 Participants
Prior Shoulder Operation(s)
No
102 Participants
n=106 Participants
Is Contralateral Shoulder in This Study
Yes
1 Participants
n=106 Participants
Is Contralateral Shoulder in This Study
No
105 Participants
n=106 Participants
Functional Demand of Operated Shoulder
Low
9 Participants
n=106 Participants
Functional Demand of Operated Shoulder
Medium
46 Participants
n=106 Participants
Functional Demand of Operated Shoulder
High
51 Participants
n=106 Participants
Concomitant Diseases
Yes
0 Participants
n=106 Participants
Concomitant Diseases
No
106 Participants
n=106 Participants
Does The Patient Take Pain/Anti-Inflammatory Medication?
Non-Narcotic Analgesics · Daily
1 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Non-Narcotic Analgesics · Weekly
10 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Non-Narcotic Analgesics · Monthly
2 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Non-Narcotic Analgesics · No
36 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Narcotic Analgesics · Daily
1 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Narcotic Analgesics · Weekly
1 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Narcotic Analgesics · Monthly
0 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Narcotic Analgesics · No
47 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
NSAIDs · Daily
2 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
NSAIDs · Weekly
5 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
NSAIDs · Monthly
4 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
NSAIDs · No
38 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Steroids · Daily
0 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Steroids · Weekly
1 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Steroids · Monthly
0 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Does The Patient Take Pain/Anti-Inflammatory Medication?
Steroids · No
48 Participants
n=49 Participants • Not all enrolled patients had preoperative data available
Patient Injury
Sustained Injury
25 Participants
n=106 Participants
Patient Injury
Chronic Degeneration of the Rotator Cuff
81 Participants
n=106 Participants
Rotator Cuff Defect
Small (< 1 cm)
7 Participants
n=106 Participants
Rotator Cuff Defect
Medium (1-3 cm)
63 Participants
n=106 Participants
Rotator Cuff Defect
Large (4-5cm)
29 Participants
n=106 Participants
Rotator Cuff Defect
Massive (<5cm)
7 Participants
n=106 Participants
Tendons Involved (e.g., torn) Supra; Infra
Supra, Infra
57 Participants
n=106 Participants
Tendons Involved (e.g., torn) Supra; Infra
Supra, Subscap
33 Participants
n=106 Participants
Tendons Involved (e.g., torn) Supra; Infra
Supra
8 Participants
n=106 Participants
Tendons Involved (e.g., torn) Supra; Infra
Supra, Infra, Subscap
7 Participants
n=106 Participants
Tendons Involved (e.g., torn) Supra; Infra
Subscap
1 Participants
n=106 Participants
Procedure Performed
Single Row Repair
1 Participants
n=106 Participants
Procedure Performed
Double Row Repair
105 Participants
n=106 Participants

PRIMARY outcome

Timeframe: From operation to study completion, 0-1 year

The investigator will clinically evaluate at 1 year follow-up visit if soft tissue to bone healing has occurred by the absence of device-related revisions and re-tears that were not previously reported. The following question will be asked to the investigator: "Did soft tissue to bone healing occur"? If "yes" is answered, then the soft tissue to bone healing is successful, if "no" is answered, then the soft tissue to bone healing is considered unsuccessful.

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Assessment of Performance by Analyzing Soft Tissue to Bone Healing in the Shoulder (Rotator Cuff)
Yes
105 Participants
Assessment of Performance by Analyzing Soft Tissue to Bone Healing in the Shoulder (Rotator Cuff)
No
1 Participants

SECONDARY outcome

Timeframe: From operation to study completion, 0-1 year

The Constant and Murley score is a 100-point functional shoulder assessment tool in which higher scores reflect increased function. The subjective variables are pain (15 points) and function (activities of daily living - sleep, work, recreation/sport; 20 points), for a total of 35 points. The objective variables are active range of motion (clinician assessment; 40 points) and strength (25 points), for a total of 65 points. The minimum score is 0 points (worst outcome), the maximum score possible is 100 points (best outcome).

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Constant and Murley Score
67.9 units on a scale
Standard Deviation 14.7

SECONDARY outcome

Timeframe: From operation to study completion, 0-1 year

Assessment of clinical benefits by functional outcomes measured using standard scoring systems. The EQ-5D measures 5 dimensions; mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, with a total of 5 questions. It is accompanied by the patient's self-assessment with the VAS. Each dimension is assigned one of three discrete levels for evaluation on the day of administration: Level 1 - No problems, no disability Level 2 - Some problems, moderate disability Level 3 - A lot of problems, severe disability The final score is a five digit composite of the responses ranging between 33333 - 11111 with 243 possible combinations in between. In the derived EQ-5D-5L score, the highest score is 1 (best outcome) and the lowest score is -0.573 (worst outcome).

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
EQ-5D-5L Score
0.95 units on a scale
Standard Deviation 0.104

SECONDARY outcome

Timeframe: From operation to study completion, 0-1 year

Safety will be assessed by monitoring the incidence and frequency of device and/or procedure related adverse events

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Assessment of Safety
Patients with adverse events
9 Participants
Assessment of Safety
Patients without adverse events
97 Participants

SECONDARY outcome

Timeframe: From operation to study completion, 0-1 year

The Subjective Shoulder Value is a patient's subjective shoulder assessment expressed as a percentage of an entirely normal shoulder.

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Subjective Shoulder Value
86.1 Percentage
Standard Deviation 13.3

SECONDARY outcome

Timeframe: 1 year after surgery

Does The Patient Take Pain/Anti-Inflammatory Medication?

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Pain / Anti-Inflammatory Medication
Non-Narcotic Analgesics · Daily
1 Participants
Pain / Anti-Inflammatory Medication
Non-Narcotic Analgesics · Weekly
6 Participants
Pain / Anti-Inflammatory Medication
Non-Narcotic Analgesics · Monthly
1 Participants
Pain / Anti-Inflammatory Medication
Non-Narcotic Analgesics · None
98 Participants
Pain / Anti-Inflammatory Medication
NSAIDs · Daily
0 Participants
Pain / Anti-Inflammatory Medication
NSAIDs · Weekly
4 Participants
Pain / Anti-Inflammatory Medication
NSAIDs · Monthly
0 Participants
Pain / Anti-Inflammatory Medication
NSAIDs · None
102 Participants

SECONDARY outcome

Timeframe: 1 year after surgery

Patient satisfaction was assessed 1 year after surgery. Possible answers were: very satisfied, satisfied, somewhat satisfied, disappointed.

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Patient Satisfaction
Very Satisfied
76 Participants
Patient Satisfaction
Satisfied
21 Participants
Patient Satisfaction
Somewhat Satisfied
7 Participants
Patient Satisfaction
Disappointed
2 Participants

SECONDARY outcome

Timeframe: 1 year after surgery

1 year after their surgery, patients were asked if yes or no they would have the surgery again.

Outcome measures

Outcome measures
Measure
Patients Who Received the Quattro X BroadBand
n=106 Participants
No specific interventions will be administered.
Would The Patient Have This Surgery Again?
Yes
85 Participants
Would The Patient Have This Surgery Again?
No
21 Participants

Adverse Events

Patients Who Received the Quattro X BroadBand

Serious events: 0 serious events
Other events: 9 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Patients Who Received the Quattro X BroadBand
n=106 participants at risk
No specific interventions will be administered.
Musculoskeletal and connective tissue disorders
Complex Regional Pain Syndrome
6.6%
7/106 • Number of events 7 • From surgery to last assessment 1 year postoperatively
Adverse Events were collected retrospectively from the patients medical notes and prospectively at the 1 year follow up visit.
Musculoskeletal and connective tissue disorders
Re-Tear
0.94%
1/106 • Number of events 1 • From surgery to last assessment 1 year postoperatively
Adverse Events were collected retrospectively from the patients medical notes and prospectively at the 1 year follow up visit.
Musculoskeletal and connective tissue disorders
Pain and Loss of Strength
0.94%
1/106 • Number of events 1 • From surgery to last assessment 1 year postoperatively
Adverse Events were collected retrospectively from the patients medical notes and prospectively at the 1 year follow up visit.

Additional Information

Julie Nicoux

Zimmer Biomet

Phone: +33672613502

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place