Brazilian Diabetes Prevention Program: Pilot Study

NCT ID: NCT05689658

Last Updated: 2024-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-15

Study Completion Date

2023-10-31

Brief Summary

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To structure a Brazilian Diabetes Prevention Program based on guidance for changing lifestyle promoted by the American Diabetes Prevention Program, using materials already developed by the Brazilian Ministry of Health and contextualizing it to the Brazilian Public Health System (SUS) and evaluating its effectiveness in a multicentric randomized clinical trial with 220 pre-diabetic patients and a follow up of 3 months. Outcomes are diet quality and time of physical activity. Health care professionals' perceptions regarding its incorporation into clinical practice will also be evaluated.

Detailed Description

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This is a multicentric randomized clinical study coordinated by the Hospital Beneficência Portuguesa in São Paulo-Brazil and made possible by PROADI-SUS (SUS Institutional Development Support Program).

The study's objective is the Brazilian Diabetes Prevention Program development based on guidance for changing lifestyle promoted by the American Diabetes Prevention Program, using materials already developed by the Brazilian Ministry of Health and contextualizing it to the Brazilian Public Health System (SUS).

The program will not include a multidisciplinary orientation, but the prescription will have a multi-professional vision. The objective is to bring the multi-team together to discuss different aspects of the same intervention, such as accessibility, motivation, contexts, and needs, so that the program, to be guided by the nutritionist, can also be recognized and supported by the other teammates.

Once the program is defined, the research teams from the collaborating centers will be trained and qualified. 220 individuals with pre-diabetes will be included in the study and followed for 3 months. Outcomes are diet quality and time of physical activity. Health care professionals' perceptions regarding its incorporation into clinical practice will also be evaluated.

Conditions

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PreDiabetes Prediabetic State

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Brazilian Diabetes Prevention Program Group

The program will be based on the American Diabetes Prevention Program (DPP), whose published results are used as a reference for prediabetic care patients in the Brazilian Diabetes Guideline. In order to reach the weight loss goal estimated at 0.5 to 1 Kg per week and 150 minutes of moderate physical activity per week, the program will offer individual and group visits, qualitative guidelines for improving diet, lifestyle and self-care.

Group Type EXPERIMENTAL

Brazilian Diabetes Prevention Program

Intervention Type BEHAVIORAL

A Program structured in 7 visits (in group and individual) to guide the improvement of diet quality, self-care, and practice of physical activity

Diet Group

Diet prescription for weight loss

Group Type ACTIVE_COMPARATOR

Diet

Intervention Type BEHAVIORAL

Hypocaloric diet prescription

Interventions

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Brazilian Diabetes Prevention Program

A Program structured in 7 visits (in group and individual) to guide the improvement of diet quality, self-care, and practice of physical activity

Intervention Type BEHAVIORAL

Diet

Hypocaloric diet prescription

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Body mass index greater than or equal to 24kg/m2
* Have one of the following criteria: (CDC criteria for participating in the DPP)

1. Diagnosis of prediabetes or
2. Fasting blood glucose between 100-125mg/dl or blood glucose 2h after oral glucose tolerance test between 140 and 199mg/dl or HbA1c between 5.7 and 6.4% (maximum test date: last 3 months) or
3. Previously diagnosed with gestational diabetes or
4. High risk on the CDC prediabetes risk test
* With Internet access
* With personal cell phone access
* No prior nutritional monitoring (6 months)
* Live at least 60 minutes from the survey call center

Exclusion Criteria

* Diagnosis of Diabetes Mellitus
* In secondary prevention for cardiovascular disease
* HIV patient with detectable viral load (amount of virus greater than 40 copies per ml of blood)
* Presence of illnesses that could seriously reduce your life expectancy or your ability to participate in the study
* Refuse to participate in the study (signing the Free and Informed Consent Form)
* Participation in another Randomized Clinical Trial whose objective interferes with the primary outcome of this research, such as diet quality and physical activity level
* Pregnant and lactating women
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beneficência Portuguesa de São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hospital Universitário Professor Edgard Santos - HUPES

Salvador, Estado de Bahia, Brazil

Site Status

Hospital de Clínicas de Goiania

Goiânia, Goiás, Brazil

Site Status

Universidade Federal de Viçosa

Viçosa, Minas Gerais, Brazil

Site Status

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Universidade Federal do Tocantins

Palmas, Tocantins, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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PROVEN-Dia

Identifier Type: -

Identifier Source: org_study_id

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