A Study to Learn About Abrocitinib in Adult Patients With Moderate to Severe Atopic Dermatitis.

NCT ID: NCT05689151

Last Updated: 2025-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

183 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-09

Study Completion Date

2027-12-31

Brief Summary

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The purpose of this study is to learn about the safety and effects of Abrocitinib in the real-life clinical setting given for the treatment of moderate to severe atopic dermatitis. Atopic dermatitis, or AD, is a long-lasting disease that causes inflammation, redness, and irritation of the skin.

This study is seeking participant who are older than 18 years with moderate-to-severe chronic AD. Participants must have no underlying medical conditions that prevent them from taking Abrocitinib.

All participants in this study will receive Abrocitinib as a tablet once daily. They can take Abrocitinib and use medicated topical treatment for AD at the same time.

We will examine the experiences of patients receiving the study medicine. This will help us determine if the study medicine is safe and helps in treating AD.

Participants will take part in this study for 24 months. During this time, they will visit the study clinic about 5 times (about 1 time every 4 to 6 months).

Detailed Description

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Conditions

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Atopic Dermatitis Eczema

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Abrocitinib

Study Drug for Observational Data Collection

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients older than 18 years of age at inclusion.
* Patients with clinical diagnosis of moderate-to-severe chronic atopic dermatitis (also referred to as atopic eczema) at inclusion according to the investigator and eligible for abrocitinib according to its marketing approval.
* Patients that have been informed of the study procedures and have signed the consent.

Exclusion Criteria

* Patients for whom abrocitinib is contraindicated.
* Patients unable to follow and respect the study procedures and judged inapt to respond to the questions required for the study due to linguistical, psychological, social, or geographical reasons.
* Patients not affiliated to the French social security system.
* Patients deprived of liberty, under guardianship, or unable to provide oral consent.
* Patients participating in a clinical study assessing a medicinal treatment (patients can participate in registries and observatories).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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CHU Amiens-Picardie - Site Nord

Amiens, Somme, France

Site Status RECRUITING

CHU Besancon - Hopital Jean Minjoz

Besançon, , France

Site Status RECRUITING

Polyclinique Reims Bezannes

Bezannes, , France

Site Status RECRUITING

Chu Bordeaux Hopital Saint Andre

Bordeaux, , France

Site Status RECRUITING

CHU Brest Hopital Morvan

Brest, , France

Site Status RECRUITING

CHU de Caen

Caen, , France

Site Status RECRUITING

Ch de Calais

Calais, , France

Site Status RECRUITING

Ch William Morey

Chalon-sur-Saône, , France

Site Status RECRUITING

CHU Clermont Ferrand - Hopital Gabriel Montpied

Clermont-Ferrand, , France

Site Status RECRUITING

Chu Estaing

Clermont-Ferrand, , France

Site Status RECRUITING

Hopital Henri Mondor

Créteil, , France

Site Status RECRUITING

Chu Dijon

Dijon, , France

Site Status RECRUITING

Hopital Franco Britannique

Levallois-Perret, , France

Site Status RECRUITING

Hopital Claude Huriez

Lille, , France

Site Status RECRUITING

CH de Martigues

Martigues, , France

Site Status RECRUITING

CHU Montpellier

Montpellier, , France

Site Status RECRUITING

Hopital Emile Muller

Mulhouse, , France

Site Status RECRUITING

Hopital Hotel Dieu

Nantes, , France

Site Status RECRUITING

Hopital Cochin

Paris, , France

Site Status RECRUITING

Hopital Tenon

Paris, , France

Site Status RECRUITING

Hopital Saint Louis (APHP) - Service Hematologic Senior

Paris, , France

Site Status RECRUITING

CHU Lyon Sud

Pierre-Bénite, , France

Site Status RECRUITING

Hopital Pontchaillou

Rennes, , France

Site Status RECRUITING

Ch de Romans Sur Isere

Romans-sur-Isère, , France

Site Status RECRUITING

Hopital Charles Nicolle

Rouen, , France

Site Status RECRUITING

Chi Poissy Saint Germain En Laye

Saint-Germain-en-Laye, , France

Site Status RECRUITING

Hopital Bégin

Saint-Mandé, , France

Site Status RECRUITING

Hopital Larrey

Toulouse, , France

Site Status RECRUITING

Ch de Valenciennes

Valenciennes, , France

Site Status RECRUITING

CHU Nancy

Vandœuvre-lès-Nancy, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Pfizer CT.gov Call Center

Role: CONTACT

1-800-718-1021

Related Links

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https://pmiform.com/clinical-trial-info-request?StudyID=B7451096

To obtain contact information for a study center near you, click here.

Other Identifiers

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ADAIR

Identifier Type: OTHER

Identifier Source: secondary_id

B7451096

Identifier Type: -

Identifier Source: org_study_id

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