Residual or Recurrent Obstruction After Septal Myectomy

NCT ID: NCT05687487

Last Updated: 2023-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

56 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-01

Study Completion Date

2021-02-01

Brief Summary

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The goal of this observational study is to report the outcomes after septal myectomy in young children and infants and identify the mechanisms of residual or recurrent obstruction after surgery. in The main question\[s\] it aims to answer are:

* What is the early and mid-term results of septal myectomy in young children and infants with severe and extensive obstructive hypertrophic cardiomyopathy (HCM)?
* What are the mechanisms of residual or recurrent obstruction?

Echocardiography and clinical course of children and infants under the age of 14 who underwent septal myectomy for hypertrophic obstructive cardiomyopathy from January 2013 to December 2020 will be followed up.

Detailed Description

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Conditions

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Hypertrophic Obstructive Cardiomyopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of hypertrophic obstructive cardiomyopathy (HOCM)
* Age young than 14 years
* Patients who have undergone septal myectomy

Exclusion Criteria

* older than 14 years old;
* secondary left ventricular hypertrophy (LVH) related to subaortic stenosis or aortic stenosis.
Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jun Yan

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Dong S, Du C, Song J, Dong J, Meng H, Xu H, Sun Y, Zou M, Li S, Yan J. Residual or recurrent obstruction after septal myectomy in young children and infants with hypertrophic cardiomyopathy: cohort study. Int J Surg. 2023 Jun 1;109(6):1699-1707. doi: 10.1097/JS9.0000000000000426.

Reference Type DERIVED
PMID: 37165977 (View on PubMed)

Other Identifiers

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2020-I2M-C&T-B-060

Identifier Type: -

Identifier Source: org_study_id

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