Effectiveness of Incentive Spirometer and Diaphragmatic Breathing Exercise on ABG Measures in Post-CABG Patients

NCT ID: NCT05684679

Last Updated: 2023-01-18

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-04-15
• Study Completion Date: 2019-08-25

Brief Summary

The rate of pulmonary complications following Coronary artery bypass graft (CABG) is high. Early pulmonary exercises are important in preventing this complication following cardiac surgery. This study aimed to investigate the effectiveness of incentive spirometer (IS) and diaphragmatic breathing exercise (DBE) on the alteration of arterial blood gas (ABG) measures. The study was based on a two-arm, parallel-group, randomized comparative design. Thirty patients who underwent CABG enrolled in the study based on inclusion and exclusion criteria, randomly allocated into either of the groups, IS Group or DBE Group. IS Group and DBE Group underwent chest physiotherapy with IS and DBE, respectively. ABG measures, including PH of blood, partial pressure of arterial oxygen molecule (PaO2), and partial pressure of arterial carbon dioxide (PaCO2), was assessed using an ABG analyzer at baseline (pre-operation), day1 post-operation, and day2 post-operation. The significance level was kept constant for all statistical analyses at 95%.

Detailed Description

Coronary artery bypass graft (CABG) is one of common treatment procedures performed worldwide. Evidence suggest that every year more than 1 million CABG procedure has been performed. Pulmonary complications are one of the most common consequence post CABG.

The incidence of atelectasis after heart operation with cardiopulmonary bypass is still 80-84% in spite of careful fluid & respiratory management. The basic problem in respiratory care of post-surgical patient is atelectasis leading to hypoxemia causing alteration in arterial blood gases (ABGs). Associated with atelectasis are widening alveolar - arterial O2 gradient (as right to left intrapulmonary shunting increases) decrease ventilation perfusion ratio, decrease functional residual capacity and decrease compliance. Chest physiotherapy is routinely used after major abdominal & cardiothoracic surgery to prevent these pulmonary complications following operation.

To date, there is a variable view about the effectiveness of these two primary breathing exercise techniques (incentive spirometer and diaphragmatic breathing exercise). 10-12 Hence an effort to systematically study the effectiveness of these is attempted. Thus, the current study aimed to determine the efficacy of incentive spirometer and diaphragmatic breathing exercises in addition to conventional chest physiotherapy on alteration of ABG measures in patients with post CABG. This study hypothesized that there will be a significant difference between the effect of the IS and DBE on ABG alteration in post CABG patients.

Conditions

Post Coronary Artery Bypass Grafting

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

IS Group

• Patients were instructed to utilize an incentive spirometer in the sitting or half lying position as taught preoperatively.

• 3 to 5 consecutive breath with the spirometer were interspersed between period of quite breathing.
• Duration 10-15 minutes/session.

Group Type: EXPERIMENTAL

Incentive spirometer plus Chest physiotherapy

Intervention Type: OTHER

Incentive spirometer was given to IS group. However, a conventional chest physiotherapy was given to both groups in the optimal position.

DBE Group

• Patients were advised to do diaphragmatic breathing exercise in the sitting or half lying position as taught preoperatively.

• 3 to 5 consecutive deep breath were interspersed between period of quite breathing.
• Duration 10-15 minutes/session.

Group Type: EXPERIMENTAL

Diaphragmatic breathing exercise plus Chest physiotherapy

Intervention Type: OTHER

Diaphragmatic breathing exercise was given to DBE group. In addition, a conventional chest physiotherapy was given in the optimal position.

Interventions

Incentive spirometer plus Chest physiotherapy

Incentive spirometer was given to IS group. However, a conventional chest physiotherapy was given to both groups in the optimal position.

Intervention Type: OTHER

Diaphragmatic breathing exercise plus Chest physiotherapy

Diaphragmatic breathing exercise was given to DBE group. In addition, a conventional chest physiotherapy was given in the optimal position.

Intervention Type: OTHER

Other Intervention Names

Huffing, Coughing, Upper and lower limbs active exercises; Huffing, Coughing, Upper and lower limbs active exercises

Eligibility Criteria

Inclusion Criteria

• The patient with post-CABG,
• Aged between 40 and 60 years,
• Had forced expiratory volume in 1 second (FEV1) <70% of predicted value,
• Showed FEV1/forced vital capacity (FVC) ratio >0.8,
• Weight equal or exceeded the ideal body weight by less than 20%, and
• Patient co-operation.

Exclusion Criteria

• Aged more than 60 years,
• Weight equal or exceeded the ideal body weight by more than 20%,
• Post-operative respiratory treatment exceeding 20 hours,
• History of Chronic obstructive pulmonary disease (COPD) /thoracic surgery including CABG,
• had thoracic anomalies/unstable angina,
• Developed hemodynamic complication, and
• Non-cooperative/neurological debilitated patient.

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

King Saud University

OTHER

Sponsor Role: lead

Responsible Party

AMIR IQBAL

Prinicipal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

AMIR IQBAL, MPT

Role: PRINCIPAL_INVESTIGATOR

King Saud University, Riyadh, Saudi Arabia

Locations

Rehabilitation Research Chair, Department of Rehabilitation Sciences, king Saud University

Riyadh, Riyadh 11433, Saudi Arabia

Countries

Saudi Arabia

Other Identifiers

RRC-2019-13

Identifier Type: -

Identifier Source: org_study_id