Online Personalized Intervention for the Prevention of Anxiety.

NCT ID: NCT05682365

Last Updated: 2023-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

2000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-30

Study Completion Date

2024-08-31

Brief Summary

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Objective: To design, develop and evaluate an online personalized intervention based on a risk algorithm for the universal prevention of anxiety disorders in the general population.

Methods: Randomized controlled trial, with two parallel arms and 12 months follow-up. The entire process of recruitment, randomization, intervention and follow-up will be carried out from a web platform designed for the study (web prevANS). Through a communication campaign, where announcements and informative videos will be produced, and through the dissemination on prevANS website, 2,000 Spanish and Portuguese adult participants without anxiety in the baseline of the study will be recruited. The participants will be randomly assigned to the prevANS intervention, which will be self-guided and can be implemented from the prevANS web or from the participants' Smartphone (through an APP), or to a control group. The prevANS intervention will have different intensities depending on the risk level of the population, evaluated from the already validated risk algorithm for anxiety: predictA. Participants with a low risk of anxiety will receive information on their level and profile (risk factors) of anxiety and psychoeducational information periodically. Participants with moderate and high risk of anxiety will also receive information on their risk level and profile, but will also include a cognitive-behavioral training (problem solving, decision-making, handling thoughts / concerns and emotions and communicational skills). Both groups of risk will work towards manage stressors and enhance protective factors. The control group will not receive any intervention, but they will fill out the same questionnaires as in the intervention group. The main result will be the incidence of new cases of anxiety disorders measured by CIDI, and the secondary results will be the reduction of anxiety (GAD-7) and depression (PHQ-9) symptoms, of the risk probability of anxiety and depression (predictA and predictD algorithms) and improvement of quality of life measured by SF-12 and EuroQol, and cost-effectiveness and cost-utility.

Detailed Description

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Conditions

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Anxiety Disorders

Keywords

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Anxiety Disorders Primary prevention Randomized controlled trial m-Health e-Health

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Control group

In this arm, participants will continue receiving the usual care from their health providers. However, they will not receive any intervention, but they will fill out the same questionnaires as in the intervention group.

Group Type NO_INTERVENTION

No interventions assigned to this group

prevANS intervention

In this arm, participants will receive an online personalized intervention to prevent anxiety disorders based on a risk predictive algorithm (predictA).

Group Type EXPERIMENTAL

prevANS intervention

Intervention Type BEHAVIORAL

prevANS intervention will be self-guided and can be implemented from the prevANS web or from the participants' Smartphone (through an APP). The prevANS intervention will have different intensities depending on the risk level of the population, evaluated from the already validated risk algorithm for anxiety: predictA. Participants will be classified as moderate-high or low risk of anxiety. Both groups of risk will receive information on their level and profile (risk factors) of anxiety and psychoeducational information periodically; also, they will work towards manage stressors and enhance protective factors. However, participants with moderate-high risk of anxiety will also receive a cognitive-behavioral training (problem solving, decision-making, handling thoughts / concerns and emotions and communicational skills).

Interventions

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prevANS intervention

prevANS intervention will be self-guided and can be implemented from the prevANS web or from the participants' Smartphone (through an APP). The prevANS intervention will have different intensities depending on the risk level of the population, evaluated from the already validated risk algorithm for anxiety: predictA. Participants will be classified as moderate-high or low risk of anxiety. Both groups of risk will receive information on their level and profile (risk factors) of anxiety and psychoeducational information periodically; also, they will work towards manage stressors and enhance protective factors. However, participants with moderate-high risk of anxiety will also receive a cognitive-behavioral training (problem solving, decision-making, handling thoughts / concerns and emotions and communicational skills).

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* GAD-7 \<10 at baseline
* GAD-7 ≥10 at baseline and a negative diagnosis of anxiety disorders by CIDI

Exclusion Criteria

* Not have a smartphone and internet for personal use
* Unable to speak Spanish
* Documented terminal illness
* Documented cognitive impairment
* Documented serious mental illness (psychosis, bipolar, addictions, etc.)
* Being involved in any psychological intervention or treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Agencia Estatal de Investigación (AEI)

UNKNOWN

Sponsor Role collaborator

Institute of Health Carlos III (ISCIII)

UNKNOWN

Sponsor Role collaborator

Institute of Biomedical Research in Málaga (IBIMA)

UNKNOWN

Sponsor Role collaborator

European Regional Development Fund

OTHER

Sponsor Role collaborator

University of Malaga

OTHER

Sponsor Role lead

Responsible Party

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Patricia Moreno Peral

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Patricia Moreno-Peral, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Malaga

Locations

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Facultad de Psicología y Logopedia

Málaga, , Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Patricia Moreno-Peral, PhD

Role: CONTACT

Phone: +34951030534

Email: [email protected]

Sonia Conejo-Cerón, PhD

Role: CONTACT

Phone: +34951030534

Email: [email protected]

Facility Contacts

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Patricia Moreno-Peral, Dr

Role: primary

References

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Moreno-Peral P, Rodriguez-Morejon A, Bellon JA, Garcia-Huercano C, Martinez-Vispo C, Campos-Paino H, Galan S, Reyes-Martin S, Sanchez Aguadero N, Rangel-Henriques M, Motrico E, Conejo-Ceron S. Effectiveness of a universal personalized intervention for the prevention of anxiety disorders: Protocol of a randomized controlled trial (the prevANS project). Internet Interv. 2023 Jun 22;34:100640. doi: 10.1016/j.invent.2023.100640. eCollection 2023 Dec.

Reference Type DERIVED
PMID: 38023964 (View on PubMed)

Other Identifiers

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PID2020-119652RA-I00

Identifier Type: -

Identifier Source: org_study_id