Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health

NCT ID: NCT05681325

Last Updated: 2023-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-25

Study Completion Date

2024-07-12

Brief Summary

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Aim of the study:

This study aims to evaluate the antioxidant and beneficial effects of matcha tea daily intake on periodontal health.

Objectives:

* To evaluate the salivary level of antioxidants (catalase, total antioxidant capacity) after matcha tea intake compared to green tea over a period of one month.
* To evaluate the clinical periodontal parameters including bleeding on probing (BOP), probing pocket depth (PPD) and plaque index (PI) after matcha tea intake compared to green tea over a period of one month.
* To evaluate the salivary levels of IL-1B after matcha tea intake compared to green tea over a period of one month.

Detailed Description

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Conditions

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Gingival Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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green tea group

Mahmood Green Tea Sri Lanka. It will be given 2 cups / day for 30 days.

Group Type ACTIVE_COMPARATOR

green tea

Intervention Type DIETARY_SUPPLEMENT

It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.

matcha tea group

Jade Leaf Organic Japanese Matcha, USA. It will be given 2 cups / day for 30 days.

Group Type EXPERIMENTAL

matcha tea

Intervention Type DIETARY_SUPPLEMENT

It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.

Interventions

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green tea

It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.

Intervention Type DIETARY_SUPPLEMENT

matcha tea

It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* • having at least 20 teeth,

* underwent no medical treatment during the last 3 months before examination and sampling,
* non-smoker,
* no history of systemic disease,
* gingivitis patient (having \>10% bleeding sites with no PPD \>3 mm).

Exclusion Criteria

* • wore orthodontic appliances,

* pregnant or currently in the breast-feeding period,
* periodontitis patient,
* smoker,
* has a history of systemic disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hayder Raad Abdulbaqi

OTHER

Sponsor Role lead

Responsible Party

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Hayder Raad Abdulbaqi

professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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HIND KAREEM, BDS

Role: STUDY_DIRECTOR

University of Baghdad

Locations

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Universality of Baghdad, College of dentistry

Baghdad, , Iraq

Site Status

Countries

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Iraq

References

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Zhang Y, Kang N, Xue F, Qiao J, Duan J, Chen F, Cai Y. Evaluation of salivary biomarkers for the diagnosis of periodontitis. BMC Oral Health. 2021 May 17;21(1):266. doi: 10.1186/s12903-021-01600-5.

Reference Type BACKGROUND
PMID: 34001101 (View on PubMed)

Kolackova T, Kolofikova K, Sytarova I, Snopek L, Sumczynski D, Orsavova J. Matcha Tea: Analysis of Nutritional Composition, Phenolics and Antioxidant Activity. Plant Foods Hum Nutr. 2020 Mar;75(1):48-53. doi: 10.1007/s11130-019-00777-z.

Reference Type BACKGROUND
PMID: 31832980 (View on PubMed)

Other Identifiers

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matcha on periodontal health

Identifier Type: -

Identifier Source: org_study_id