Neuropsychological Profiles of Children With Duchenne Muscular Dystrophy and Its Effects on Motor Functions
NCT ID: NCT05661071
Last Updated: 2022-12-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
74 participants
OBSERVATIONAL
2022-05-11
2023-03-01
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Duchenne Muscular Dystrophy
Children with Duchenne Muscular Dystrophy (DMD) between the ages of 7 and 16 who have been diagnosed with DMD as a result of genetic testing
Modified Mini Mental Test:
To assess the cognitive function of children
The Controlled Oral Word Association Test
To assess the cognitive function of children
The Central Nervous System Vital Signs
To assess the cognitive function of children
Conners' Parent Rating Scale-48 (Parent Report)
To assess attention-deficit/hyperactivity disorder
Child Behavior Checklist 6-18 ages (Parent Report)
To assesses both child adaptive behaviors and problem behaviors.
Strengths and Difficulties Questionnaire (Self-Reported)
It is a brief emotional and behavioural screening questionnaire for children and young people.
Brooke Lower Extremity Functional Classification
To determine the functional status of the lower extremity
Motor Function Measurement-32 Items
To assessment of motor function and progression of weakness in neuromuscular disorders
Four Square Step Test
A test of dynamic balance and coordination that clinically assesses the participant's ability to step over objects forward, sideways, and backwards.
Six Minutes Walk Test
It evaluates the walking function and physical capacity of children at the submaximal level.
Timed Performance Test
10 meters Walk\& Run Test, Gower's(from a supine to a standing position), Right\& Left Leg Standing, Ascent/Descent of 4 Steps
Typically Developed Children
Typically Developed Children with similar physical characteristics between the ages of 7 and 16
Modified Mini Mental Test:
To assess the cognitive function of children
The Controlled Oral Word Association Test
To assess the cognitive function of children
The Central Nervous System Vital Signs
To assess the cognitive function of children
Conners' Parent Rating Scale-48 (Parent Report)
To assess attention-deficit/hyperactivity disorder
Child Behavior Checklist 6-18 ages (Parent Report)
To assesses both child adaptive behaviors and problem behaviors.
Strengths and Difficulties Questionnaire (Self-Reported)
It is a brief emotional and behavioural screening questionnaire for children and young people.
Interventions
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Modified Mini Mental Test:
To assess the cognitive function of children
The Controlled Oral Word Association Test
To assess the cognitive function of children
The Central Nervous System Vital Signs
To assess the cognitive function of children
Conners' Parent Rating Scale-48 (Parent Report)
To assess attention-deficit/hyperactivity disorder
Child Behavior Checklist 6-18 ages (Parent Report)
To assesses both child adaptive behaviors and problem behaviors.
Strengths and Difficulties Questionnaire (Self-Reported)
It is a brief emotional and behavioural screening questionnaire for children and young people.
Brooke Lower Extremity Functional Classification
To determine the functional status of the lower extremity
Motor Function Measurement-32 Items
To assessment of motor function and progression of weakness in neuromuscular disorders
Four Square Step Test
A test of dynamic balance and coordination that clinically assesses the participant's ability to step over objects forward, sideways, and backwards.
Six Minutes Walk Test
It evaluates the walking function and physical capacity of children at the submaximal level.
Timed Performance Test
10 meters Walk\& Run Test, Gower's(from a supine to a standing position), Right\& Left Leg Standing, Ascent/Descent of 4 Steps
Eligibility Criteria
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Inclusion Criteria
* Being between the ages of 7-16,
* Not to have any diagnosed chronic disease,
* Not having lost yet the ability to write and draw as required by neuropsychological assessments,
* Cooperate with the physiotherapist and be able to comply with their instructions.
Exclusion Criteria
* Have had any injury and/or surgery to the lower/upper extremities in the last 6 months, which may prevent the performance of motor function tests.
7 Years
16 Years
MALE
Yes
Sponsors
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Hacettepe University
OTHER
Responsible Party
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Esra Aldırmaz
Principal Investigator
Principal Investigators
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İpek Gürbüz, Assc. Prof.
Role: STUDY_DIRECTOR
Hacettepe University
Locations
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Hacettepe University, Faculty of Physical Therapy and Rehabilitation, Pediatric Neuromuscular Diseases Unit for physiotherapy and rehabilitation
Ankara, , Turkey (Türkiye)
Countries
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References
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Aldirmaz E, Bulut N, Yilmaz O, Alemdaroglu-Gurbuz I. Cognitive and emotional-behavioural outcomes of Turkish Duchenne muscular dystrophy population and its association with motor function. Eur J Paediatr Neurol. 2024 Sep;52:86-94. doi: 10.1016/j.ejpn.2024.08.004. Epub 2024 Aug 18.
Other Identifiers
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GO22/310
Identifier Type: -
Identifier Source: org_study_id