Comparison of Triamcinolone With Pentoxifylline and Vitamin- E Efficacy in the Treatment of Stage 2 and 3 Oral Submucous Fibrosis
NCT ID: NCT05660694
Last Updated: 2022-12-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
40 participants
INTERVENTIONAL
2020-01-01
2021-09-30
Brief Summary
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Detailed Description
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It was a randomized control clinical trial to compare efficacy of injection steroids versus pentoxifylline and vitamin E in the treatment of stage 2 and 3 OSF patient. Total 40 patients who presented with signs and symptoms of OSF were enrolled in our study that was evaluated over the period of (January 2020 to September 2021). Parameters taken in the study were age and mouth opening. Descriptive statistics and paired t-test were used for statistical analysis.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Group 1: Triamcinolone
Injection steroid Triamcinolone 400mg with lidocaine 1:1 was given twice a week for 4 weeks in bi-lateral buccal mucosa in multiple sites
Triamcinolone
Comparison of Triamcinolone with Pentoxifylline and Vitamin- E Efficacy
Group 2: Pentoxifylline with Vitamin E
Pentoxifylline 40mg twice a day along with vitamin E supplement one tablet per day for 4 weeks
Pentoxifylline with Vitamin E
Comparison of Triamcinolone with Pentoxifylline and Vitamin- E Efficacy
Interventions
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Triamcinolone
Comparison of Triamcinolone with Pentoxifylline and Vitamin- E Efficacy
Pentoxifylline with Vitamin E
Comparison of Triamcinolone with Pentoxifylline and Vitamin- E Efficacy
Eligibility Criteria
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Inclusion Criteria
* Patients willing to quit their tobacco chewing habit, gutkha areca nut smoking
* Patients who are ready to attend regular follow-ups
Exclusion Criteria
* Patients with any evidence of cardiac, gastrointestinal, kidney, metabolic disorders, pregnant and lactating women's
* Patients with any co-existing disorder of the orofacial region other than OSF which may interfere with the study protocol
ALL
Yes
Sponsors
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Altamash Institute of Dental Medicine
OTHER
Responsible Party
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Abhishek Lal
Dr. Abhishek Lal
Locations
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Altamash Institute of Dental Medicine
Karachi, Sindh, Pakistan
Countries
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Other Identifiers
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Treatment of OSF stage 2 and 3
Identifier Type: -
Identifier Source: org_study_id