Trial Outcomes & Findings for ModPG3 Adult/Ped ISO 81060-2:2018 Study Protocol (NCT NCT05654714)

NCT ID: NCT05654714

Last Updated: 2025-11-19

Results Overview

BP readings for all subjects will be calculated separately for systolic and diastolic blood pressure. At least three paired blood pressure values shall be taken for each subject. ISO 81060-2:2018/Amd 1:2020 Non-invasive sphygmomanometers - Part 2: Clinical investigation of intermittent automated measurement type

Recruitment status

TERMINATED

Target enrollment

152 participants

Primary outcome timeframe

Day 1 (up to 1 hour)

Results posted on

2025-11-19

Participant Flow

Participant milestones

Participant milestones
Measure
Blood Pressure Readings
The study will be conducted in 2 parts. * Part 1 will test subjects using the ModPG3 Investigational device with the SureBP algorithm enabled. * Part 2 will test subjects using the ModPG3 Investigational device with the StepBP algorithm enabled. The study requires three observers. The first two observers take auscultatory readings that are averaged to use as reference blood pressures. The third observer operates the ModPG3 investigational device and records the readings for that device. The two clinicians taking reference readings will be blinded to each other's readings and to the investigational device readings. ModPG3 Investigational Device: • Connex Vital Sign Monitor with ModPG3 * Laptop * Blood Pressure Data Collection Software (not used for test report analysis) * USB cable * Power strip * Welch Allyn FlexiPort Reusable Blood Pressure Cuffs Auscultatory Equipment: • Reference Sphygmomanometer1 * Reference Cuffs2 * Dual Auscultatory Stethoscope * Tape measure * Stopwatch
Overall Study
STARTED
152
Overall Study
COMPLETED
134
Overall Study
NOT COMPLETED
18

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Blood Pressure Readings
n=152 Participants
The study will be conducted in 2 parts. * Part 1 will test subjects using the ModPG3 Investigational device with the SureBP algorithm enabled. * Part 2 will test subjects using the ModPG3 Investigational device with the StepBP algorithm enabled. The study requires three observers. The first two observers take auscultatory readings that are averaged to use as reference blood pressures. The third observer operates the ModPG3 investigational device and records the readings for that device. The two clinicians taking reference readings will be blinded to each other's readings and to the investigational device readings. ModPG3 Investigational Device: • Connex Vital Sign Monitor with ModPG3 * Laptop * Blood Pressure Data Collection Software (not used for test report analysis) * USB cable * Power strip * Welch Allyn FlexiPort Reusable Blood Pressure Cuffs Auscultatory Equipment: • Reference Sphygmomanometer1 * Reference Cuffs2 * Dual Auscultatory Stethoscope * Tape measure * Stopwatch
Age, Customized
3 - 17 years
57 Participants
n=152 Participants
Age, Customized
>= 18 years
95 Participants
n=152 Participants
Sex: Female, Male
Female
64 Participants
n=152 Participants
Sex: Female, Male
Male
88 Participants
n=152 Participants
Region of Enrollment
Italy
152 participants
n=152 Participants
Arm Circumference of ≥12-55 cm
152 Participants
n=152 Participants

PRIMARY outcome

Timeframe: Day 1 (up to 1 hour)

Population: The study was terminated due to errors in the algorithm planned for data processing and analysis. A validated post processing algorithm for the raw data files was never finalized, so no blood pressure measurements needed for analysis are available. There is no data available to populate the outcome measure.

BP readings for all subjects will be calculated separately for systolic and diastolic blood pressure. At least three paired blood pressure values shall be taken for each subject. ISO 81060-2:2018/Amd 1:2020 Non-invasive sphygmomanometers - Part 2: Clinical investigation of intermittent automated measurement type

Outcome measures

Outcome data not reported

Adverse Events

Blood Pressure Readings

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jessica Gregory

Baxter

Phone: N/A

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place