Assessing Speech Perception and Amplification Benefit During Infancy

NCT ID: NCT05653999

Last Updated: 2025-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

36 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-03-10

Study Completion Date

2025-05-28

Brief Summary

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The goal of this project is to compare aided and unaided speech discrimination among infants with hearing loss and a cohort of infants with typical hearing.

Working Hypothesis: Among this group of infants with hearing loss, performance will be significantly better when infants are tested while using amplification (i.e., aided condition) compared to when tested without amplification (i.e., unaided condition). Infants fit with optimally programmed amplification will perform similarly to the infants with typical hearing on speech discrimination tasks.

Detailed Description

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Conditions

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Hearing Loss Children With Hearing Differences Amplification Speech Perception

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Normal Hearing

Group 1 will consist of approximately 20 infants with normal hearing. This cohort will have passed their newborn hearing screenings and will pass audiologic measurements on the day of testing. Audiologic measurements include tympanometry to determine middle ear function and otoacoustic emissions testing to determine cochlear integrity.

No interventions assigned to this group

Hearing Loss

Group 2 will consist of approximately 20 infants with diagnosed bilateral sensorineural hearing loss ranging from mild to severe. These infants will also pass audiologic measures on the day of testing (tympanometry as described in group 1), currently use bilateral air-conduction hearing aids, and are enrolled in early intervention services.

Hearing Aids

Intervention Type DEVICE

Hearing aids will be used by infants with a diagnosed sensorineural hearing loss.

Interventions

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Hearing Aids

Hearing aids will be used by infants with a diagnosed sensorineural hearing loss.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Children between the ages of 6 months and 36 months (inclusive) at the time of enrollment.
* English is the primary spoken language in the home
* Demonstrated ability to complete a conditioned head turn via visual reinforcement audiometry (VRA)
* If normal hearing

-Normal hearing sensitivity bilaterally
* If Hearing Loss

* Children with diagnosis of bilateral sensorineural hearing ranging from mild to severe
* Children currently using hearing aids
* Children currently enrolled in intervention

Exclusion Criteria

* Children born earlier than 35 weeks gestation
* Children with abnormal tympanometry on the day of testing
* Children with concerns of secondary disabilities
* Children with Auditory Neuropathy
* Concerns of hearing loss in normal hearing children
Minimum Eligible Age

6 Months

Maximum Eligible Age

36 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sonova AG

INDUSTRY

Sponsor Role collaborator

University of Colorado, Denver

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kristin M Uhler, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Colorado School of Medicine

Locations

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University of Colorado School of Medicine - Speech Perception Over Time Lab

Aurora, Colorado, United States

Site Status

Countries

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United States

Other Identifiers

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22-2169

Identifier Type: -

Identifier Source: org_study_id

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