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Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

NCT ID: NCT05650008

Last Updated: 2023-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-01

Study Completion Date

2023-10-10

Brief Summary

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The objective of this study is to assess the effects of intrathecal local anesthetics on left ventricular global longitudinal strain (LVGLS) using transthoracic echocardiography (TTE).

Detailed Description

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Conditions

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Left Ventricular Dysfunction Spinal Anesthetics Causing Adverse Effects in Therapeutic Use Global Cardiac Wall Motion Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Intrathecal local anesthesia

Administration of local anesthetic into intrathecal space to achieve surgical anesthesia

Intervention Type DRUG

Other Intervention Names

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Spinal anesthesia

Eligibility Criteria

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Inclusion Criteria

* Adult patients undergoing elective knee and hip replacements under spinal anesthesia

Exclusion Criteria

* Patients who do not wish to consent
* Patients with contraindications to TTE
* Patients with reduced left ventricular systolic function as defined by LV ejection fraction \< 50% on pre-operative echocardiography
* Patients with body mass index greater than 40
* Non-English-speaking subjects
* Cognitively impaired adults
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Milton S. Hershey Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Shayne Michael Roberts

Associate Professor, Department of Anesthesiology and Perioperative Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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21263

Identifier Type: -

Identifier Source: org_study_id