A Study in Male and Female Adult Participants With Chronic Rhinosinusitis With Nasal Polyps In the Greater Gulf Region

NCT ID: NCT05649813

Last Updated: 2024-07-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

148 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-20

Study Completion Date

2024-06-14

Brief Summary

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Primary Objective:

\- To describe the clinical characteristics of participants with chronic rhinosinusitis with nasal polyps (CRSwNP) in terms of disease severity, Type 2 inflammation-related comorbidities (such as asthma and allergic rhinitis), other associated comorbidities, and treatments used in a real-world setting

Secondary Objectives:

* Describe the progression in treatment outcomes at different visits (baseline, 3 months, 6 months, and 12 months).
* To assess the healthcare resource utilization of participants with CRSwNP in countries of the Gulf region (number of visits, emergency room (ER), surgery, etc).

Detailed Description

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Conditions

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Chronic Rhinosinusitis With Nasal Polyps

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CRSwNP

Participants with CRSwNP in the Gulf region

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male or female participants.
* Participants diagnosed with chronic rhinosinusitis with nasal polyps (CRSwNP) for at least one year prior to study start.
* Participants diagnosed with CRSwNP according to criteria of American Academy of Otolaryngology-Head and Neck Surgery (i.e. the diagnosis is confirmed in medical records by clinical symptoms and objective evidence of nasal polyps by using anterior rhinoscopy and nasal endoscopy when available and/or computed tomography (CT) scan).
* Participants should be at least 18 years old.
* Participants must have signed an informed consent.

Exclusion Criteria

* Participants with chronic rhinosinusitis without nasal polyps (CRSsNP)
* Pregnant/breastfeeding participants or participants planning for a pregnancy.
* Participants participating in other interventional clinical trials involving any investigational drug.
* Participants with granulomatous diseases such as vasculitis or sarcoidosis. The above information is not intended to contain all considerations relevant to a potential participation in a clinical trial.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sanofi

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Sciences & Operations

Role: STUDY_DIRECTOR

Sanofi

Locations

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Investigational Site Number: 01

Kuwait City, , Kuwait

Site Status

Countries

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Kuwait

Other Identifiers

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U1111-1279-3286

Identifier Type: REGISTRY

Identifier Source: secondary_id

OBS17627

Identifier Type: -

Identifier Source: org_study_id

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