Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients with Versus Without Intestinal Polyps

NCT ID: NCT05648240

Last Updated: 2024-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-23

Study Completion Date

2026-02-28

Brief Summary

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The study authors hypothesize that in patients with intestinal polyps, tumor cells could disseminate and circulating factors could be secreted by the polyp. These two parameters could become biomarkers to refine the follow-up of patients and to establish targeted therapeutic strategies.

Detailed Description

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Conditions

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Colorectal Cancer Neoplasm Metastasis Disseminated Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with polyps

Blood test

Intervention Type OTHER

Venous blood samples taken at the moment of colonoscopy to test for biomarkers

Patients without polyps

Blood test

Intervention Type OTHER

Venous blood samples taken at the moment of colonoscopy to test for biomarkers

Interventions

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Blood test

Venous blood samples taken at the moment of colonoscopy to test for biomarkers

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient to be examined by colonoscopy
* The patient must be a member or beneficiary of a health insurance plan

Exclusion Criteria

* The subject is participating in a category 1 interventional study, or is in a period of exclusion determined by a previous study
* The subject signals their opposition to participate in the study
* It is impossible to give the subject informed information
* The patient is under safeguard of justice or state guardianship
* Patient pregnant or breastfeeding
* History of proven cancerous disease
* Patient followed for a chronic inflammatory bowel disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-François BOURGAUX

Role: PRINCIPAL_INVESTIGATOR

CHU de Nimes

Locations

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CHU de Nîmes

Nîmes, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Jean-François BOURGAUX

Role: CONTACT

Phone: 04.66.68.81.85

Email: [email protected]

Facility Contacts

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Anissa Megzari

Role: primary

Jean-François BOURGAUX

Role: backup

Other Identifiers

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NIMAO/2022-1/JFB01

Identifier Type: -

Identifier Source: org_study_id