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The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa

NCT ID: NCT05645848

Last Updated: 2022-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-31

Study Completion Date

2025-01-31

Brief Summary

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Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.

Detailed Description

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Conditions

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Placenta Previa Vaginal Bleeding Antepartum Hemorrhage

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Ultrasonography

Abdominal ultrasound in pregnant women with placenta previa

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Pregnant women ≥ 28 weeks.
* Diagnosed to have placenta previa by ultrasound

Exclusion Criteria

* Women with complicated pregnancies (e.g. preeclampsia, diabetes mellitus and cardiac, renal, antiphospholipid syndrome).
* Women with premature rupture of membrane.
* Women who will refuse to participate.
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Ismail Omar Mohammed Ali

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kamal M Zahran, professor

Role: STUDY_CHAIR

department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt

Mohamed K Ali, doctor

Role: STUDY_DIRECTOR

department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt

Mohamed M Abd-allah, doctor

Role: STUDY_DIRECTOR

department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt

Ismael O Ali, resident

Role: PRINCIPAL_INVESTIGATOR

department of obstetrics and gynecology, faculty of medicine, Assuit University, Egypt

Central Contacts

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Ismael O Ali, resident

Role: CONTACT

Phone: +201033039300

Email: [email protected]

References

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Wu S, Kocherginsky M, Hibbard JU. Abnormal placentation: twenty-year analysis. Am J Obstet Gynecol. 2005 May;192(5):1458-61. doi: 10.1016/j.ajog.2004.12.074.

Reference Type BACKGROUND
PMID: 15902137 (View on PubMed)

Shaamash AH, Ali MK, Attyia KM. Intramuscular 17alpha-hydroxyprogesterone caproate to decrease preterm delivery in women with placenta praevia: a randomised controlled trial. J Obstet Gynaecol. 2020 Jul;40(5):633-638. doi: 10.1080/01443615.2019.1645099. Epub 2019 Oct 31.

Reference Type BACKGROUND
PMID: 31670998 (View on PubMed)

Shazly SA, Badee AY, Ali MK. The use of multiple 8 compression suturing as a novel procedure to preserve fertility in patients with placenta accreta: case series. Aust N Z J Obstet Gynaecol. 2012 Aug;52(4):395-9. doi: 10.1111/j.1479-828X.2012.01449.x. Epub 2012 Jun 9.

Reference Type BACKGROUND
PMID: 22681562 (View on PubMed)

Nagase Y, Matsuzaki S, Endo M, Hara T, Okada A, Mimura K, Hiramatsu K, Kakigano A, Nakatsuka E, Miyake T, Takiuchi T, Ueda Y, Tomimatsu T, Kimura T. Placenta previa with posterior extrauterine adhesion: clinical features and management practice. BMC Surg. 2021 Jan 6;21(1):10. doi: 10.1186/s12893-020-01027-9.

Reference Type BACKGROUND
PMID: 33407322 (View on PubMed)

Dashe JS. Toward consistent terminology of placental location. Semin Perinatol. 2013 Oct;37(5):375-9. doi: 10.1053/j.semperi.2013.06.017.

Reference Type BACKGROUND
PMID: 24176163 (View on PubMed)

Love CD, Fernando KJ, Sargent L, Hughes RG. Major placenta praevia should not preclude out-patient management. Eur J Obstet Gynecol Reprod Biol. 2004 Nov 10;117(1):24-9. doi: 10.1016/j.ejogrb.2003.10.039.

Reference Type BACKGROUND
PMID: 15474239 (View on PubMed)

Other Identifiers

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placenta previa bleeding rate

Identifier Type: -

Identifier Source: org_study_id