The Role of Artificial Intelligence in the Treatment of Abdominal Aortic Aneurysms
NCT ID: NCT05643664
Last Updated: 2022-12-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2023-01-01
2024-12-31
Brief Summary
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Detailed Description
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Thus, in order to reduce the frequency of embolic complications, it is important for the surgeon to determine a "safe" zone for applying a clamp to the aorta and main vessels. Thus, artificial intelligence (AI) can be used to interpret and analyze images of aneurysms that allow automatic quantitative measurements and determination of the exact characteristics of morphology and hydrodynamics, as well as the presence of intraluminal blood clots and calcifications. Analysis based on artificial intelligence can lead to the development of computational programs for predicting the development of aneurysms and the risk of their rupture, as well as postoperative outcomes. Artificial intelligence can also be used to determine the "safe" areas of aortic clamping. (Artificial intelligence in abdominal aortic aneurysm).
Adam and co-authors trained a neural network to detect and estimate the maximum outer diameter of aneurysms using a database of 489 CT angiographs of abdominal aortic aneurysms. AI has achieved a level of performance and accuracy suitable for clinical practice, and with the use of more CT images, further improvement in accuracy is expected (Pre-surgical and Post-surgical Aortic Aneurysm Maximum Diameter Measurement: Full Automation by Artificial Intelligence). In a study by Fujiwara et al. 145 non-contrast CT scans with suspected aneurysm were retrospectively collected. Initially, AI was trained by manually segmenting CT images. Image processing was used to determine the abdominal aortic aneurysm area and to automatically measure the size. This method has shown that AI is a useful tool for fully automatic detection and measurement of aneurysm diameter. (Fully automatic detection and measurement of abdominal aortic aneurysm using artificial intelligence). Florent Lalys and his coauthor. an automatic fast and universal algorithm for determining an intraluminal thrombus was developed. The method was tested on pre- and postoperative CT scans of the abdominal aorta and iliac artery of 145 patients and consists in determining the central line and segmentation of the aortic lumen, an optimized stage of pretreatment and the use of a 3D model (Generic thrombus segmentation from pre- and post-operative CTA).
Taking into account the references already available in some studies of the use of artificial intelligence for the treatment of cardiovascular diseases, its use is seen as a promising method for making decisions in determining "safe" clamping zones in the surgical treatment of abdominal aortic aneurysms, which will reduce the frequency of postoperative complications.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
2. In the first group, the aortic and main artery clamping zone is determined by the surgeon intraoperatively.
In the second group, before surgery, multispiral computed tomography data is evaluated using artificial intelligence and the definition of "safe" areas of aortic and main artery clamping is performed. Intraoperatively, clamping is performed in the settlement zones.
PREVENTION
NONE
Study Groups
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Standart technology
the zone of aortic and main artery clamping is determined by the surgeon intraoperatively.
prosthetics of the abdominal aorta
aneurysmectomy is performed with prosthetics of the abdominal aorta using the standard technology.
Artificial intellect
The multispiral computed tomography data is evaluated using artificial intelligence and the definition of "safe" zones of aortic and main artery clamping is performed. Intraoperatively, clamping is performed in the settlement zones.
prosthetics of the abdominal aorta after determining the safe zones of clamping
aneurysmectomy is performed with prosthetics of the abdominal aorta using the standard technology. Before surgery, multispiral computed tomography data is evaluated using artificial intelligence and safe zones of aortic and arterial clampings are determined. Intraoperatively, clamping is performed in the settlement zones.
Interventions
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prosthetics of the abdominal aorta
aneurysmectomy is performed with prosthetics of the abdominal aorta using the standard technology.
prosthetics of the abdominal aorta after determining the safe zones of clamping
aneurysmectomy is performed with prosthetics of the abdominal aorta using the standard technology. Before surgery, multispiral computed tomography data is evaluated using artificial intelligence and safe zones of aortic and arterial clampings are determined. Intraoperatively, clamping is performed in the settlement zones.
Eligibility Criteria
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Inclusion Criteria
* Patients who have agreed to participate in this study
Exclusion Criteria
* Chronic decompensated "pulmonary" heart;
* Severe hepatic or renal insufficiency (bilirubin \>35 mmol/l, glomerular filtration rate \<60 ml/min);
* Polyvalent drug allergy;
* Malignant oncological diseases in the terminal stage with a predicted life span of up to 6 months;
* Acute cerebrovascular accident;
45 Years
75 Years
ALL
No
Sponsors
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Meshalkin Research Institute of Pathology of Circulation
NETWORK
Responsible Party
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Locations
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Alexander A Gostev
Novosibirsk, Novosibirskaya Obl, Russia
Federal State Institution Academician E.N.Meshalkin Novosibirsk State Research Institute Of Circulation Pathology Rusmedtechnology
Novosibirsk, , Russia
Novosibirsk Research Institute of Circulation Pathology
Novosibirsk, , Russia
E. Meshalkin National Medical Research Center
Novosibirsk, , Russia
Countries
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Central Contacts
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Other Identifiers
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NRICP-16/11/22
Identifier Type: -
Identifier Source: org_study_id