The Reliability and Validity of the L-test in Patients With Multiple Sclerosis

NCT ID: NCT05641714

Last Updated: 2023-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

68 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-15

Study Completion Date

2023-01-16

Brief Summary

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Walking safely inside or outside is an important function in patients with Multiple Sclerosis (PwMS) that affects their daily life activity and participation. Loss of functional mobility is the major component of walking disorders in PwMS. Therefore, it is important to evaluate functional mobility.

Many functional mobility tests have been used for PwMS; however, these tests generally focus on walking speed and endurance. On the other hand, the L test, a variation of the timed up and go test (TUG), is a functional mobility measurement tool that extends the total walking distance to 20 meters and also requires the patients to turn both clockwise and counterclockwise.

Although L the test is an easy-to-use, short-term test method that evaluates higher-level components of functional mobility such as turns and transfers, to our knowledge, no study has systematically examined the reliability and validity of the L test in PwMS yet. In addition, the cut-off times that best discriminate PwMS from healthy people and fallers with non-fallers with Multiple Sclerosis (MS) have not been reported. Therefore, this study planned to investigate the reliability, validity, and discrimination of the L test in PwMS.

Detailed Description

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At baseline, the L test, Timed Up and Go test, 10 meter walk test, six minute walk test, and the timed 360 turn test will be applied to the Multiple Sclerosis group. The L test will be repeated after seven days after the first application in PwMS. Healthy controls are going to perform only the L test.

Conditions

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Multiple Sclerosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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multiple sclerosis

Patients with Multiple Sclerosis

L test

Intervention Type OTHER

The test includes standing up from a chair, walking in a straight line for 3 m, turning to the right, walking in a straight line for 7 m, turning around, walking back 7 m along the same line, turning to the left, walk 3 m in a straight line to the chair, and then sit down.

Timed Up and Go test

Intervention Type OTHER

The test requires the individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again.

10 meter walk test

Intervention Type OTHER

In the test, the clinician measures the time taken to walk a distance of 10 m from a standing position. Participants are asked to walk along a 14 m long walkway.

Six Minute Walk Test

Intervention Type OTHER

This test measures the distance (in m) that an individual is able to walk at a comfortable speed for 6 minutes. Starting from a standing position, participants walk continuously around two pylons placed 30 m apart for 6 minutes. The distance is recorded end of the test.

The timed 360° turn test

Intervention Type OTHER

Each participant turns around in place in a standing position for both sides.

healthy controls

healthy controls

L test

Intervention Type OTHER

The test includes standing up from a chair, walking in a straight line for 3 m, turning to the right, walking in a straight line for 7 m, turning around, walking back 7 m along the same line, turning to the left, walk 3 m in a straight line to the chair, and then sit down.

Interventions

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L test

The test includes standing up from a chair, walking in a straight line for 3 m, turning to the right, walking in a straight line for 7 m, turning around, walking back 7 m along the same line, turning to the left, walk 3 m in a straight line to the chair, and then sit down.

Intervention Type OTHER

Timed Up and Go test

The test requires the individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again.

Intervention Type OTHER

10 meter walk test

In the test, the clinician measures the time taken to walk a distance of 10 m from a standing position. Participants are asked to walk along a 14 m long walkway.

Intervention Type OTHER

Six Minute Walk Test

This test measures the distance (in m) that an individual is able to walk at a comfortable speed for 6 minutes. Starting from a standing position, participants walk continuously around two pylons placed 30 m apart for 6 minutes. The distance is recorded end of the test.

Intervention Type OTHER

The timed 360° turn test

Each participant turns around in place in a standing position for both sides.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age at least 18 years,
* Neurologist-diagnosed Multiple Sclerosis,
* Expanded Disability Status Scale (EDSS) score between 0-5,
* No MS exacerbation within the last 3 months,
* Use of stable medication in the last 3 months.

Exclusion Criteria

* Having any vision, hearing, or perception problems that may affect the research results,
* Having an orthopedic problem that will prevent walking and standing
* Having a cardiovascular, pulmonary, or hormonal disorder
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gazi University

OTHER

Sponsor Role lead

Responsible Party

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Kader Eldemir

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Gazi University

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Kim JS, Chu DY, Jeon HS. Reliability and validity of the L test in participants with chronic stroke. Physiotherapy. 2015 Jun;101(2):161-5. doi: 10.1016/j.physio.2014.09.003. Epub 2014 Oct 28.

Reference Type BACKGROUND
PMID: 25555897 (View on PubMed)

Deathe AB, Miller WC. The L test of functional mobility: measurement properties of a modified version of the timed "up & go" test designed for people with lower-limb amputations. Phys Ther. 2005 Jul;85(7):626-35.

Reference Type BACKGROUND
PMID: 15982169 (View on PubMed)

Eldemir K, Eldemir S, Ozkul C, Irkec C, Guclu-Gunduz A. Reliability and validity of the L test in people with multiple sclerosis. Physiotherapy. 2025 Mar;126:101429. doi: 10.1016/j.physio.2024.101429. Epub 2024 Sep 24.

Reference Type DERIVED
PMID: 39541755 (View on PubMed)

Other Identifiers

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1-MS-L-Test-reliability

Identifier Type: -

Identifier Source: org_study_id

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