Evaluation of Safety and Efficacy of IPL Presets for Cutaneous Lesions

NCT ID: NCT05630690

Last Updated: 2023-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-04

Study Completion Date

2024-04-30

Brief Summary

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Single-center, Prospective, Open-Label with Before-After Study Design. Each subject will receive up to three (3) consecutive treatments at 1-month interval. Treatment presets will be determined by the SMART Camera system and approved by the physician. Follow-up will take place at 1 month following the last treatment. Skin and lesion attributes will be examined by the SMART system and the physician on each visit and at follow-up.

Detailed Description

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Up to 20 healthy subjects, aged 21-80 years old with visible textural lesions including but not limited to Lentigines, Rosacea, and Age spots / Telangiectasia on the face or décolletage that wish to improve their skin appearance. Each patient should have at least 3 treatment areas (e.g. left cheek, right cheek, forehead, nose, chin, upper/lower décolletage) that contain at least one type of lesion.

Following the SMART Camera analysis, the system will suggest treatment presets. The physician will decide whether to use the treatment presets recommended by the AI system or modify them, based on the safety and efficacy of the suggested treatment presets.

Conditions

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Vascular Lesion Pigmented Lesions

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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IPL with smart diagnostic handpiece

Standard IPL module which has FDA clearance (K083733) for a wide range of indications including vascular and pigmented lesions. The Universal IPL handpiece (HP) operates at a spectrum of 400-1,200 nm with 7 different cut-off filters and 2 different notch filters that can be easily inserted into the handpiece to treat different conditions.

The SMART Camera is a novel add-on skin diagnostic (SD) tool. The SD module includes a proprietary spectral camera embedded in a handpiece, and proprietary computer vision-based algorithms designed to process the spectral information and to determine the skin attributes and optimal treatment IPL preset.

Group Type EXPERIMENTAL

IPL with smart diagnostic handpiece

Intervention Type DEVICE

treatment with IPL following diagnostic with SMART system

Interventions

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IPL with smart diagnostic handpiece

treatment with IPL following diagnostic with SMART system

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Healthy Female/Male, age 21-80
2. Fitzpatrick skin type I-V
3. Presence of visible textural lesions including but not limited to:

1. Lentigines
2. Age spots / Telangiectasia (Photoaging treatment)
3. Rosacea (Erythematotelangiectatic rosacea and papulopustular rosacea)
4. Telangiectasia
4. Patients should have at least 3 treatment areas of the following: right cheek, left cheek, forehead, nose, chin, or upper/lower décolletage.
5. Able to read, understand and provide written Informed Consent.
6. Able and willing to comply with the treatment/follow-up schedule and requirements.
7. Willing to have digital photographs taken of all of the treatment areas before, during, and after the treatment.
8. Willing to refrain from using any prescription or over-the-counter topical creams used for the treatment of veins or pigmented lesions in the treatment area during the study period.
9. Willing to protect and/or have very limited sun exposure and use an approved sunscreen of SPF 50 or higher in the treatment area, every day for the duration of the study.
10. Agree not to undergo any other procedure(s) in the same treatment areas during the study.
11. Women of child-bearing age are required to be using a reliable method of birth control (such as an intrauterine device, birth control pills, condom with spermicidal, NuvaRing, partner with vasectomy, or abstinence) at least 1 month prior to first treatment and throughout the course of the study.

Exclusion Criteria

1. Previous treatments in the same area/s within twelve months prior to screening.
2. Fitzpatrick skin type VI.
3. Pregnant, intending to become pregnant during the course of study, less than 3 months postpartum or less than 6 weeks after completion of breastfeeding.
4. Exposure to the sun or artificial tanning during 3-4 weeks prior to treatment. Any remaining suntan, sunburn, or artificial tanning products.
5. Active infections in the treatment area.
6. Dysplastic nevi.
7. Significant concurrent skin conditions or any inflammatory skin conditions.
8. Active cold sores, open lacerations, or abrasions in the treatment area.
9. Chronic or cutaneous viral, fungal or bacterial diseases.
10. Treatment should not be attempted on patients with a history or concurrent condition of skin cancer or pre-cancerous lesions in the treatment area
11. Tattoos in the treatment area.
Minimum Eligible Age

21 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Emek Medical Center

OTHER

Sponsor Role collaborator

Lumenis Be Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Lumenis Be Ltd.

Yokneam Illit, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Rula Masoud, PhD

Role: CONTACT

Phone: 0503018155

Email: [email protected]

Facility Contacts

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Rula Masoud

Role: primary

Other Identifiers

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LUM-ABU-SMRT-22-02

Identifier Type: -

Identifier Source: org_study_id