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10-year Follow-up After Tibial Tubercle Transposition

NCT ID: NCT05629754

Last Updated: 2023-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-18

Study Completion Date

2024-12-31

Brief Summary

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Patellofemoral pain is a common complaint especially in young adults. It can be caused by patellar maltracking. Part of this is a patella alta. When patellar maltracking is the cause of the problem and conservative therapy fails, surgery, a tibial tuberosity transposition, may be considered. Most research has been done in patients with recurrent patella luxation. However, in patients without luxation, research is scarce.

It is known that patients with patella alta have an increased risk of developing patellofemoral chondropathy due to increased pressure. With this study, we aim to investigate whether and how a tibial tuberosity transposition in patients with patella alta and no instability affects the degree of patellofemoral chondropathy and patient satisfaction after 10 years. This will allow us to educate patients regarding long-term outcomes better.

Detailed Description

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Anterior knee pain is a common complaint, especially in younger and active adults. An obvious source for anterior knee pain is patellar maltracking, which is often associated with patella alta (a high-riding patella). Due to maltracking, the cartilage of the patella can face a greater amount of pressure, which can cause cartilage damage. When conservative treatment fails, a surgical intervention can be considered. One of the surgical options is performing a tibial tubercle transfer (TTT), where the patella is being distalized and medialized. As a result, the improvement in patellar tracking will reduce the pressure on the retropatellar cartilage. The TTT has been proven effective in patients with patellar instability but less is known about patients without instability. Specifically, whether these patients face a higher risk of developing retropatellar cartilage damage ('retropatellar chondropathy') due to this intervention is currently unknown.

The primary aim of this study is to determine the incidence and the degree of retropatellar chondropathy 10 years after a TTT in patients with anterior knee pain without patellar instability. The secondary aim is to evaluate the long-term patient reported outcomes (PROMs) 10 years after a TTT in patients with anterior knee pain without patellar instability.

Conditions

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Anterior Knee Pain Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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MRI, radiological assessment

MRI and radiological assessment of the involved knee

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 80 years
* Participated in an earlier cohort study
* Underwent a tibial tubercle transposition between 2012 and 2015
* Preoperative MRI available

Exclusion Criteria

* No preoperative MRI is available
* Patellar-related surgery after the initial surgery
* Female patients that are (expecting to be) pregnant
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Noordwest Ziekenhuisgroep

OTHER

Sponsor Role collaborator

Centre for Orthopaedic Research Alkmaar

OTHER

Sponsor Role lead

Responsible Party

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Joyce L Benner, PhD

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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JL Benner, PhD

Role: PRINCIPAL_INVESTIGATOR

Noordwest Ziekenhuisgroep

Locations

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Noordwest Ziekenhuisgroep

Alkmaar, North Holland, Netherlands

Site Status

Countries

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Netherlands

References

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Bayoumi T, van Duijvenbode DC, Benner JL, Boerma-Argelo KDS, Stavenuiter MHJ, van der List JP. Clinical Improvement Is Achieved Following Tibial Tubercle Distomedialization for Patellar Maltracking and Patella Alta Without Instability. Arthrosc Sports Med Rehabil. 2021 Jun 15;3(3):e845-e853. doi: 10.1016/j.asmr.2021.01.027. eCollection 2021 Jun.

Reference Type BACKGROUND
PMID: 34195653 (View on PubMed)

Other Identifiers

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NL82613.029.22

Identifier Type: -

Identifier Source: org_study_id