Etiology of Anemia Among Preschool Children in Ethiopia

NCT ID: NCT05626647

Last Updated: 2022-11-29

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 590 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-11-01
• Study Completion Date: 2022-09-04

Brief Summary

This study aims to determine the etiology of anemia among preschool children in selected regions of Ethiopia. The study is a longitudinal observational study to assess the determinant factors of anemia in two different seasons.

The main questions it aims to answer are:

1. What is the prevalence and etiology of anemia in the two different (Post and Pre-harvest) seasons?

2. What is the strength of the interaction between anemia and each of the determinant factors being considered?

The participant's dietary intake and anthropometric measurement have been assessed, and biological samples (Blood and Stool) were collected to determine the prevalence of anemia and the factors contributing to it.

Detailed Description

Background: Although the country made a significant change in the burden of malnutrition in all its forms in the past two decades, the issue remains unacceptably high across all regions of Ethiopia. The national prevalence of anemia among children 6-59 months was very high 57% and one of the public health concerns in 2016. Although the country is known as a data-rich country, in some specific indicators, there is a lack of data and evidence to alleviate the nutritional gaps through an informed decision-making process. In this particular case, there is a lack of evidence relating to child anemia in Ethiopia, especially since there is no comprehensive information about the determinant factors of anemia.

Objective: The objective of the current survey is to determine the etiology of anemia and its public health implications among under-five children in selected ecological zones of Ethiopia at different seasons.

Method: This survey will be a community-based, longitudinal panel study and will be conducted in two different (post-harvest and pre-harvest) seasons in the 2014 Ethiopian calendar year. A nationally representative sample was calculated and allocated to three purposely selected regions (Amhara, Southern Nation, Nationalities, and Peoples' Region (SNNPR), and Somali) in consideration of three different ecological zones (lowlands, midlands, and highlands). The study population will be children aged 6 - 59 months with caregivers/mothers with a sample size of 1212 under-five children from 1212 households. The indicators collected for the survey are dietary intake, anthropometric measurement, and biological samples (Blood and Stool).

Expected benefit: The findings of this survey will provide information on the etiology of anemia that will inform short-term policy decisions, especially for case-specific nutrition-sensitive interventions, and that will contribute to long-term policy decisions for comprehensive nutrition intervention programs.

Conditions

Anemia

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: OTHER

Eligibility Criteria

Inclusion Criteria

• Children 6-53 months during the baseline survey and who have stayed more than 6 months in the selected household of the Amhara or SNNPR or Somali regions of Ethiopia and have no plan to move from the study area during the study period

Exclusion Criteria

• Children older than the youngest child between 6-53 months of age (If more than one eligible child is in the Household) during the baseline survey.
• Children with severe illness
• Guests
• If participants lose their willingness to participate in this study

• Minimum Eligible Age: 6 Months
• Maximum Eligible Age: 59 Months
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ethiopian Public Health Institute

OTHER_GOV

Sponsor Role: collaborator

Addis Ababa University

OTHER

Sponsor Role: collaborator

Oklahoma State University

OTHER

Sponsor Role: lead

Responsible Party

Solomon Hailu

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Barbara J Stocker, Prof

Role: STUDY_CHAIR

Oklahoma State University

Locations

Ethiopian Public Health Institute

Addis Ababa, , Ethiopia

Countries

Ethiopia

References

Anemia prevalence among preschool children in 2016 is 57%. EDHS, "Ethiopian Demography and Health Survey 2016, Central Statistical Agency (CSA).," Addis Ababa, Ethiopia, 2016.

Reference Type: RESULT

Other Identifiers

IRB-21-505

Identifier Type: -

Identifier Source: org_study_id