Pediatric Cardiac Surgery Comparing Short 24-hour Antibiotic Prophylaxis to Extended Antibiotic Prophylaxis
NCT ID: NCT05612542
Last Updated: 2023-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
400 participants
OBSERVATIONAL
2019-09-02
2020-03-02
Brief Summary
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Numerous recent recommendations show a benefit of a reduced duration of antibiotic prophylaxis in surgery, particularly in pediatrics.
The study focuses on the incidence of postoperative infection by comparing antibiotic prophylaxis with 2nd generation cephalosporin (G2G) for 48 hours to a short antibiotic prophylaxis protocol limited to 24 hours.
The bacterial infections considered were those said to be care-related, according to the criteria of the French Society of Anesthesia and Intensive Care if they occurred within the 3 months postoperative interval and were not present before the surgery:
* sepsis
* superficial or deep surgical site infection (mediastinitis, sternitis, scar infection)
* catheterization infection,
* urinary tract infection or
* respiratory infection such as pneumopathy acquired under mechanical ventilation
The hypothesis is that reducing the duration of antibiotic prophylaxis does not expose patients to an increased risk of infection and limits exposure to antibiotics
Detailed Description
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Conditions
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Keywords
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Study Design
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CASE_ONLY
RETROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Operated for cardiac surgery at the University Hospital of Strasbourg between January 2015 and June 2019, by sternal approach (sternotomy),
* Child and holders of parental authority who have not expressed, after information, their objections to the reuse of his for the purpose of this research.
Exclusion Criteria
* Child with an infection at the time of heart surgery,
* Child and parental authority holders who have expressed their objections to participating in this research
0 Years
17 Years
ALL
No
Sponsors
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University Hospital, Strasbourg, France
OTHER
Responsible Party
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Locations
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Service réanimation pédiatrique médico-chirurgicale spécialisée - CHU de Strasbourg - France
Strasbourg, , France
Countries
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Other Identifiers
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7484
Identifier Type: -
Identifier Source: org_study_id