Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
50 participants
OBSERVATIONAL
2021-02-01
2041-01-31
Brief Summary
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In SpA, the method of determination of IL17 seems to be questionable.
The determination of cytokines after stimulation of immune cells in patients with active SpA requiring a biological treatment could provide us with a tool to assist in the choice of therapy.
The aim of the study was to show the feasibility of cytokine assay following lymphocyte stimulation in active SpA requiring biological treatment. And secondly, to show the predictive character of this expression on the therapeutic response at three months after the implementation of a biological treatment.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Spondyloarthritis without biological treatment and in failure of 2 NSAIDS
Blood sample
Blood samples required to performe IL-17 Dosage
Interventions
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Blood sample
Blood samples required to performe IL-17 Dosage
Eligibility Criteria
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Inclusion Criteria
* Patients who were to benefit from the implementation of a biological treatment after failure of at least two NSAIDs.
* Patients having an active disease defined by a Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) higher than four,
Exclusion Criteria
* Having received a previous biological treatment
* Patients presenting contraindication to the implementation of these treatments.
18 Years
90 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire de Nice
OTHER
Responsible Party
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Locations
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CHU de NICE
Nice, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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22Rhumato02
Identifier Type: -
Identifier Source: org_study_id
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