Does Antibiotic Prophylaxis at Urinary Catheter Removal Prevent Urinary Tract Infections

NCT ID: NCT05577273

Last Updated: 2022-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

1000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-14

Study Completion Date

2023-08-31

Brief Summary

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At the end of most urological procedures, the doctor inserts a urethral catheter for a period of up to 5 days. According to AUA's guidelines, prophylactic antibiotic is indicated during catheter removal.

The aim of our study is to check the influence of the antibiotic treatment on urinary tract infections after catheter removal

Detailed Description

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Conditions

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Urologic Diseases Urinary Tract Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

2 arms: antibiotic prophylaxis vs no treatment
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Antibiotic prophylaxis

Single dose of p.o. antibiotic given 1 hour before catheter removal. The antibiotic of choice is Cefuroxime axetil 500 mg. For penicillin allergy, trimethoprim/sulfamethoxazole 160mg/800mg.

Group Type EXPERIMENTAL

Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)

Intervention Type DRUG

single dose of P.O. Cefuroxime Axetil 500 mg. For penicillin allergy patients, single dose of P.O. Trimethoprim/Sulfamethoxazole 160mg/800mg

No treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)

single dose of P.O. Cefuroxime Axetil 500 mg. For penicillin allergy patients, single dose of P.O. Trimethoprim/Sulfamethoxazole 160mg/800mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* performing urological operation for other reason

Exclusion Criteria

* cannot give informed consent
* \<18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Omri Schwarztuch Gildor

OTHER

Sponsor Role lead

Responsible Party

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Omri Schwarztuch Gildor

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Meir Medical Center

Kfar Saba, , Israel

Site Status

Countries

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Israel

Other Identifiers

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MMC-0048-18

Identifier Type: -

Identifier Source: org_study_id

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