TDCS Combined With CT In Opioid Use Disorder

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-01

Study Completion Date

2020-06-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of the present study is to investigate the effect of prefrontal transcranial Direct Current Stimulation (tDCS) combined with cognitive training on cognitive functions in individuals with Opioid Use Disorder (OUD). The participants will be allocated into active/sham groups (1:1) and will receive a single session of prefrontal tDCS combined with cognitive training. Outcomes of the active and sham groups will be compared.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Efficacy of Deep Transcranial Magnetic Stimulation in Patients With Opioid Use Disorder

NCT06081985

Opioid Use Disorder

COMPLETED NA

Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder

NCT05986578

Cocaine Use Disorder

RECRUITING NA

Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Substance Use Disorder

NCT06577454

Opioid Use Disorder Healthy Volunteers

SUSPENDED NA

Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders

NCT03229642

Transcranial Magnetic Stimulation Heroin Dependence

UNKNOWN NA

Non-Invasive Brain Stimulation and Substance Use

NCT03122587

Substance Use Disorders

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Opioid Use Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Participants, investigators and outcome assessors will be blinded.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Active tDCS combined with Cognitive Training

Group Type ACTIVE_COMPARATOR

transcranial Direct Current Stimulation

Intervention Type DEVICE

Participants will receive a single session of active/sham tDCS. During each session, 2 milliAmpers of active or sham tDCS will be applied for 20 minutes over the dorsolateral prefrontal cortex (right anodal/left cathodal).

Cognitive training

Intervention Type PROCEDURE

Participants will be administered Game of Dice Task concurrent with the tDCS session

Sham tDCS combined with Cognitive Training

Group Type SHAM_COMPARATOR

transcranial Direct Current Stimulation

Intervention Type DEVICE

Participants will receive a single session of active/sham tDCS. During each session, 2 milliAmpers of active or sham tDCS will be applied for 20 minutes over the dorsolateral prefrontal cortex (right anodal/left cathodal).

Cognitive training

Intervention Type PROCEDURE

Participants will be administered Game of Dice Task concurrent with the tDCS session

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

transcranial Direct Current Stimulation

Participants will receive a single session of active/sham tDCS. During each session, 2 milliAmpers of active or sham tDCS will be applied for 20 minutes over the dorsolateral prefrontal cortex (right anodal/left cathodal).

Intervention Type DEVICE

Cognitive training

Participants will be administered Game of Dice Task concurrent with the tDCS session

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Being aged between 18-65 years
* being in the maintenance phase of the OUD treatment
* naivety to tDCS
* at least 5 years of education

Exclusion Criteria

* current diagnosis of major depressive disorder
* current diagnosis or history of bipolar disorders, psychotic disorders, neurocognitive disorders, pervasive developmental disorders, mental retardation, severe neurological disorders,
* common tDCS contraindications

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No