Registry for CADASIL

NCT ID: NCT05567744

Last Updated: 2025-10-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-03

Study Completion Date

2027-10-31

Brief Summary

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This study is being done in order to create a registry (list) of people interested in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) research. It may be that you have a family member or other loved one with CADASIL, or that you may have CADASIL or are at risk. Participation means that your name will be added to a list of people who will be invited to participate in future research studies on CADASIL. Participants must be 18 years or older, and will remain on the registry until they request to be removed.

Detailed Description

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The purpose of this registry is to allow Dr. Jane Paulsen and her CADASIL research teams to contact individuals on the list who may fit a study's eligibility requirements. All individuals interested in CADASIL research who either have a family member or loved one, or are at risk themselves, are eligible to participate in this registry. Information collected as part of the registry will be used solely to determine potential participant's eligibility to participate research.

A patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves a predetermined scientific, clinical, or policy purpose(s).

Conditions

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Cerebral Autosomal Dominant Ateriopathy With Subcortical Infarcts and Leukoencephalopathy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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CADASIL Registry Participants

Have a loved one or family member with CADASIL, or anyone with or at risk for CADASIL

Registry

Intervention Type OTHER

Registry

Interventions

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Registry

Registry

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* have a loved one or a family member with CADASIL, or are at-risk for CADASIL themselves

Exclusion Criteria

* Under 18 years of age
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Wisconsin, Madison

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jane Paulsen, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Wisconsin, Madison

Locations

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University of Wisconsin

Madison, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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CADASIL Consortium

Role: CONTACT

833-795-3016

Facility Contacts

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CADASIL Consortium

Role: primary

833-795-3016

Other Identifiers

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A535100

Identifier Type: OTHER

Identifier Source: secondary_id

SMPH/NEUROLOGY/NEUROLOGY

Identifier Type: OTHER

Identifier Source: secondary_id

Protocol Version 9/22/2022

Identifier Type: OTHER

Identifier Source: secondary_id

2022-0827

Identifier Type: -

Identifier Source: org_study_id

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