Long Term Follow-up of Comparison of Clopidogrel vs. Aspirin Monotherapy After Drug-eluting Stent Implantation
NCT ID: NCT05567536
Last Updated: 2022-10-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
5530 participants
OBSERVATIONAL
2014-03-01
2028-12-31
Brief Summary
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Investigators will perform a retrospective analysis of all participants enrolled in this trial will be performed, until the longest follow-up duration.
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Detailed Description
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Afterwards, the current study was planned to perform a extended follow-up of the HOST-EXAM population. The specific drug by the randomization group in the HOST-EXAM trial was not mandatory after the initial 24 months, therefore participants received medication according to the current guidelines, and according to the physicians preferences.
This is a observational, retrospective analysis of all clinical events after the randomization period. The prescribed medications and any clinical events will be evaluated.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Clopidogrel group
This group are those who received clopidogrel 75mg qd as a single antiplatelet agent therapy after PCI.
Antiplatelet Agents
Patients who received a single antiplatelet agent will be analyzed according to the prescribed antiplatelet agent
Aspirin group
This group are those who received aspirin 100mg qd as a single antiplatelet agent therapy after PCI.
Antiplatelet Agents
Patients who received a single antiplatelet agent will be analyzed according to the prescribed antiplatelet agent
Interventions
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Antiplatelet Agents
Patients who received a single antiplatelet agent will be analyzed according to the prescribed antiplatelet agent
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
19 Years
ALL
No
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Hyo-Soo Kim
Professor, Department of Internal Medicine
References
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Koo BK, Kang J, Park KW, Rhee TM, Yang HM, Won KB, Rha SW, Bae JW, Lee NH, Hur SH, Yoon J, Park TH, Kim BS, Lim SW, Cho YH, Jeon DW, Kim SH, Han JK, Shin ES, Kim HS; HOST-EXAM investigators. Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention (HOST-EXAM): an investigator-initiated, prospective, randomised, open-label, multicentre trial. Lancet. 2021 Jun 26;397(10293):2487-2496. doi: 10.1016/S0140-6736(21)01063-1. Epub 2021 May 16.
Antithrombotic Trialists' (ATT) Collaboration; Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, Buring J, Hennekens C, Kearney P, Meade T, Patrono C, Roncaglioni MC, Zanchetti A. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009 May 30;373(9678):1849-60. doi: 10.1016/S0140-6736(09)60503-1.
Other Identifiers
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1208-028-421
Identifier Type: -
Identifier Source: org_study_id
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