An Observational Study of Skin Reaction in Infants Using the Owlet Sock OSS 3.0

NCT ID: NCT05561946

Last Updated: 2022-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

43 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-12-21

Study Completion Date

2022-08-24

Brief Summary

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This multi-center, open-label, observational study will evaluate possible skin reactions associated with the wearing of the Owlet OSS 3.0 device continuously (except during sensor charging and excessive motion) up to 24 hours per day in a clinical environment.

Detailed Description

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After an informed consent process, the Owlet OSS 3.0 Sock device will be applied to the foot in accordance with the instructions for use for the device. A research team member, along with any appropriate medical personnel, will perform a baseline examination of the skin to ensure there are no preexisting skin or extremity findings which would interfere with interpretation of subsequent examinations.

A review of the medical record will be performed with the consent process to ensure that vital signs and the cardiorespiratory status of the patient is sufficiently stable for the patient to proceed with study participation. A verbal medical history from the parent may be performed in lieu of a medical record review in healthy subjects.

Subject height and weight, and measurements of the circumference of the subject's ankle and midfoot will be performed at the start of the study and recorded. Sock size will be estimated according to subject weight, per the instructions for use.

The device will be worn by the subject continuously, except during skin assessments, when devices are exchanged, or activities of daily living such as bathing and brief ambulation for toddlers.

A baseline photograph will be taken of the study subject's feet and labeled as right/left, to be kept for reference for future skin exams. Skin examinations will be performed every 4 hours on the foot where the device is placed, including with repositioning. A ±30-minute window on either side of the prescribed time will be acceptable (1 hour total) to comply with the schedule of events.

Repositioning the device to the opposite foot will occur routinely every 8 hours, or sooner if there is evidence of a skin reaction related to device wear. Again, a ±30-minute window on either side of the prescribed time will be acceptable for protocol compliance.

A photograph will be taken of the study subject's feet at baseline prior to application of the Owlet Sock OSS 3.0 device. A photograph of the initial application of the device will also be taken and documented in the study subject's record.

Documentation of the date, time, location, and result of each skin exam will be performed. Photographs of any skin reactions with a severity level of 1-7 will be taken. If any skin reactions are observed, the device will not be placed on the affected foot until the reaction has resolved and returned to baseline. The device will be applied to the unaffected foot while the affected foot reaction resolves. If the skin finding does not resolve within the allowed 8 hour window when the sock must be rotated to the opposite foot, the subject will be withdrawn from study intervention.

Conditions

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Skin Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hospitalized Infants

Hospitalized infants that are planned/scheduled to remain in-house for at least 2 days will wear the sock for a minimum of 48 hours and a maximum of 14 days.

Owlet OSS 3.0

Intervention Type DEVICE

The Owlet OSS 3.0 is worn continuously for a minimum of 48 hours and the skin where the device is worn is monitored for any skin injury/irritation

Healthy Infants

Healthy infants, accompanied by their parent or legal guardian, that are able to stay at a clinical site for 2 days to complete a minimum of 48 hours of monitoring.

Owlet OSS 3.0

Intervention Type DEVICE

The Owlet OSS 3.0 is worn continuously for a minimum of 48 hours and the skin where the device is worn is monitored for any skin injury/irritation

Interventions

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Owlet OSS 3.0

The Owlet OSS 3.0 is worn continuously for a minimum of 48 hours and the skin where the device is worn is monitored for any skin injury/irritation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Provision of signed and dated informed consent form by the legal guardian
* Stated willingness of the guardian to adhere to study procedures and availability for the duration of the study
* Anticipated to maintain continuity of study procedures under study team oversight for a minimum of 48 hours duration
* Male or female infants aged 1 month (44 weeks corrected gestational age) to 18 months, with weight between 5 and 30 lbs who will be observed in a hospital pediatric department, or other clinical site

Exclusion Criteria

* Medical conditions determined by the study subject's physician or site investigator that would prevent their participation
* Presence of any devices or medical equipment that in the opinion of the investigator would interfere with the function of the Owlet device or preclude completion of the protocol
* Patients on vasoactive medications
* Known allergic reactions to nylon, spandex, elastine or polyester film components of the device that will come into contact with skin
* Local skin disease prohibiting wearing of the device
Minimum Eligible Age

44 Weeks

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Louisiana State University Health Sciences Center Shreveport

OTHER

Sponsor Role collaborator

University of Utah

OTHER

Sponsor Role collaborator

Topaz Clinical Research

UNKNOWN

Sponsor Role collaborator

Owlet Baby Care, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alisa Niksch, MD

Role: STUDY_DIRECTOR

Study Sponsor

Locations

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TOPAZ Clinical Research

Apopka, Florida, United States

Site Status

Louisiana State University Health Shreveport

Shreveport, Louisiana, United States

Site Status

Countries

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United States

References

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World Health Organization. MHealth: New Horizons for Health through Mobile Technologies (Global Observatory for Ehealth). 1st ed., World Health Organization, 2011.

Reference Type BACKGROUND

Dangerfield MI, Ward K, Davidson L, Adamian M. Initial Experience and Usage Patterns With the Owlet Smart Sock Monitor in 47,495 Newborns. Glob Pediatr Health. 2017 Dec 4;4:2333794X17742751. doi: 10.1177/2333794X17742751. eCollection 2017.

Reference Type BACKGROUND
PMID: 29230431 (View on PubMed)

Panda SS, Panda M, Das RR, Mohanty PK. Pulse oximeter probe-induced toe injury in a neonate: A rare avoidable injury. J Clin Neonatol 2014;3:240

Reference Type BACKGROUND

Other Identifiers

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OWL 2021-01

Identifier Type: -

Identifier Source: org_study_id