Are Neutrophil-Lymphocyte Ratio, Platelet-Lymphocyte Ratio, and Systemic Immune Inflammation Score Values Indicators for Postoperative Pain?
NCT ID: NCT05558553
Last Updated: 2023-11-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
2 participants
OBSERVATIONAL
2022-09-18
2022-09-24
Brief Summary
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Detailed Description
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Postoperative pain is a result of the inflammatory response to surgical trauma. Local inflammatory mediator response triggered by surgical incision, dissection, retraction, etc. causes an increase in nociceptor sensitivity and hyperalgesia, resulting in the perception of postoperative pain. With the acute phase response caused by surgical trauma, tissue damage is brought under control, infection is limited and the healing process begins. During the inflammatory response, the level of leukocytes in the blood also changes. Neutrophil/Lymphocyte ratio (NLR), Platelet/Lymphocyte ratio (PLR) and Systemic immune inflammation score (SII) are inexpensive and easily accessible biomarkers calculated from routine hemogram parameters and shown to be helpful in disease investigations and evaluation of treatment response. In this study, the relationship between biomarkers and postoperative pain status due to surgery will be investigated
Conditions
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Study Design
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OTHER
RETROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
2. Patients with ASA status1-2-3
Exclusion Criteria
2. Patients switched to open surgery
3. Patients allergic to tramadol
4. Those allergic to paracetamol
5. Those allergic to tenoxicam
6. Patients who cannot use the patient-controlled analgesia device
7. Those with hematological disorders
8. Those receiving immunosuppressive therapy
9. Those with inflammatory disease
10. Those with gastrointestinal tumors
11. Those with rheumatic disease
12. Those with uncontrolled diabetes
13. Those with chronic organ failure
14. Those who use corticosteroids
15. Opioid users
16. Those who have recently had an attack of cholecystitis, pancreatitis
18 Years
75 Years
ALL
No
Sponsors
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Samsun University
OTHER
Responsible Party
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Senay Canikli
medical specialist (Anesthesiology and Reanimation)
Principal Investigators
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Şenay Canikli Adıgüzel
Role: STUDY_DIRECTOR
responsibl investigator
Locations
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SAMSUN UNIVERSITY Samsun Training and research hospital
Samsun, , Turkey (Türkiye)
Samsun Üniversity
Samsun, , Turkey (Türkiye)
Countries
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References
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Tasargol O. A Prospective Study on the Predictability of Propofol Injection Pain. Cureus. 2020 Feb 10;12(2):e6945. doi: 10.7759/cureus.6945.
Other Identifiers
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2022/4/11
Identifier Type: -
Identifier Source: org_study_id