Action Observation Therapy Versus Mirror Therapy on Upper Limb in Stroke

NCT ID: NCT05544747

Last Updated: 2022-12-12

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-10-01
• Study Completion Date: 2023-03-01

Brief Summary

Stroke is a medical condition which causes the cessation of blood flow to the brain cells and results in cell death and ultimately can lead to motor disorders, perception disorders, language disorders, sensory disturbances.It is well known that stroke is the leading cause of death and one of the greatest causes of long-term motor disability in adults.The incidence of stroke is increasing day by day in low-income countries as compared to high-income countries because of the effects of not using evidence-based practice in health-related conditions in low-income countries. In the last few years, several approaches have been used for the recovery of hand dexterity after stroke. Among them, the Mirror therapy, task-oriented therapy, robot-assisted rehabilitation and action observation has gained greatest attention.Action observation training is one of the new developing rehabilitation technique that targets motor learning by the activation of mirror neurons and is the most important approach that targets the motor and functional recovery in stroke patients. In action observation training, the movements are produced because of the external stimuli in which actually the visual attention recruit the cerebellar-thalamic-cortical circuit of the brain. Action observation is based on activities of the motor neuron system and they discharge mostly in association with complex tasks as compared to simple tasks.

Conditions

Stroke

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Action Observation Therapy

The patients in the action observation therapy group will be required to observe the upper limb movements or functional actions in video clips. (i.e., the observation phase) and to execute what they had observed to the best of their ability (i.e., the execution phase). Three common categories of movements and tasks will be elected in the action observation therapy protocol based on the related literature

Group Type: EXPERIMENTAL

Action Observation Therapy

Intervention Type: OTHER

following phases will be included in action observation therapy group:

1. upper limb active range of motion (AROM) exercises.

2. reaching movement or object manipulation.

3. upper limb functional tasks.

Mirror Therapy

During the mirror therapy, the patients will be seated in front of a mirror box placed at their mid-sagittal plane. The affected arm of the participants will be placed inside the mirror box and the unaffected arm in front of the mirror. The patient will be instructed to watch the mirror reflection of the movement performed by his/her unaffected hand carefully and to imagine that the movement was performed by the affected hand.

Group Type: ACTIVE_COMPARATOR

Mirror Therapy

Intervention Type: OTHER

following phases will be included in mirror therapy group:

1. AROM exercises),

2. reaching movement or object manipulation, and

3. functional task practice

Interventions

Action Observation Therapy

following phases will be included in action observation therapy group:

1. upper limb active range of motion (AROM) exercises.

2. reaching movement or object manipulation.

3. upper limb functional tasks.

Intervention Type: OTHER

Mirror Therapy

following phases will be included in mirror therapy group:

1. AROM exercises),

2. reaching movement or object manipulation, and

3. functional task practice

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Both male and female
• Middle cerebral artery stroke
• 1 to 6 months of stroke onset
• Baseline score of the Fugyl Myer Assessment is between 20 and 60 for the upper limb.
• Modified Ashworth scale with a score of 2 Ability to follow the study instructions-Mini mental state examination (MMSE) score >25

Exclusion Criteria

• Participants failing to fall in this category would be excluded from the study.
• Patients who cannot perform the active movement of the upper limb in pre-stroke condition due to musculoskeletal problems
• cardiopulmonary diseases which could hinder their ability to participate in the rehabilitation program in this study
• Patient with impaired cognition

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Ayesha Afridi, PhD*

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

Helping hand institute of rehabilitation sciences

Mansehra, , Pakistan

Site Status: RECRUITING

Countries

Pakistan

Central Contacts

Sania Syed, MS NMPT*

Role: CONTACT

Phone: +92 321 1930855

Email: saniasyed48@gmail.com

Facility Contacts

Sania Syed, MS NMPT*

Role: primary

Other Identifiers

REC-01332 Sania

Identifier Type: -

Identifier Source: org_study_id