A Study of Paravertebral Block in Thoracic Outlet Syndrome

NCT ID: NCT05544721

Last Updated: 2025-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

PHASE4

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-05

Study Completion Date

2027-08-31

Brief Summary

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This research is being done to evaluate the effects of receiving only a paravertebral block prior to first rib resection procedure versus receiving the block both pre and post procedure.

Detailed Description

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Conditions

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Thoracic Outlet Syndrome

Keywords

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First rib resection procedure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Paravertebral block pre procedure

Subjects will receive a preoperative paravertebral block only

Group Type ACTIVE_COMPARATOR

Ropivacaine

Intervention Type DRUG

0.5% 3-4 mL per level, with levels T1 and T2 will be used as the block injectate

Paravertebral block pre and post procedure

Subjects will receive one paravertebral block, administered preoperatively and one paravertebral block, administered on postoperative day 1

Group Type ACTIVE_COMPARATOR

Ropivacaine

Intervention Type DRUG

0.5% 3-4 mL per level, with levels T1 and T2 will be used as the block injectate

Interventions

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Ropivacaine

0.5% 3-4 mL per level, with levels T1 and T2 will be used as the block injectate

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

\- All Thoracic Outlet Syndrome patients scheduled for first rib resection surgery.

Exclusion Criteria

* Patients who are pregnant.
* Patients with prior first rib resection on side of presentation.
* Patients with complex regional pain syndrome (CRPS).
* Patients with brachial plexus disorder.
* Patients with cervical rib.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Houssam Farres, M.D.

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Houssam Farres, MD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Florida

Jacksonville, Florida, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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22-006685

Identifier Type: -

Identifier Source: org_study_id