A Self-management Based Survivorship Intervention for Chinese Cancer Survivors

NCT ID: NCT05534386

Last Updated: 2025-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

486 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-12

Study Completion Date

2026-12-31

Brief Summary

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This study, using a sequential multiple assessment randomized controlled trial (SMART) approach, will evaluate a cancer survivorship care intervention on physical symptom distress, weight management, self-efficacy in managing cancer and health-related quality of life among Chinese patients recently completed curative cancer treatment.

Detailed Description

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This study, using this SMART approach, will assess the effect of a cancer survivorship care intervention on physical symptom distress, self-efficacy in managing cancer, weight management and health-related quality of life among Chinese patients recently completing curative cancer treatment. First, the investigators will test the effect of a one-off, multidisciplinary team face-to-face assessment (namely, the cancer survivorship clinic) with personalized advice on symptom management, lifestyle modification and anxiety management in reducing the case prevalence of symptom distress, increasing the proportion meeting the weight management criteria, and improving self-efficacy and health-related quality of life among cancer survivors in post-treatment survivorship, in comparison to those receiving skills-based pamphlets for symptom management and lifestyle recommendations. Secondly, this study aims to explore if a step-up targeted personalized intervention is more effective for patients who continue to have symptom distress and/or not to meet the weight management criteria if patients have attended cancer survivorship clinic (i.e. the embedded adaptive intervention) in comparison to those receiving skills-based pamphlets.

Conditions

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Physical Symptom Distress Weight Management Neoplasms

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

First stage intervention: We will use a block randomization with randomly permuted block sizes of 2,4, and 6 to ensure close balance of the numbers in each arm. Participants will be randomised to the intervention group (i.e. Cancer survivorship care intervention) or control group (i.e. a set of pamphlets explaining symptoms and describing skill-based self-management for symptom management and lifestyle recommendations).

Second stage intervention: We will use a block randomization with randomly permuted block sizes of 2,4, and 6 to ensure close balance of the numbers in each arm. Participants will be randomised to continue in the trial as usual (i.e. those in the survivorship clinic arm will be asked to follow the advice given by the multidisciplinary team in the initial visit and for those in the control arm will be asked to follow the advices printed in the skill-based self-management pamphlets) or to attend a step-up targeted personalized intervention.
Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
The investigator, care provider, investigator and outcomes assessor are masked in terms of not knowing to which condition the participants will be randomized until after the completion of the baseline assessment. The outcomes assessor will break the envelope for the next eligible participant indicating if that participant is to be allocated to intervention or control arms.

The participants are masked in terms of not knowing that one intervention is hypothesized to yield larger effects than the other.

Study Groups

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First stage intervention: Cancer survivorship care intervention (CSCI)

Patients randomized to the CSCI will attend a 120-minutes survivorship clinic in which each participant will be assessed by members a multidisciplinary team comprising a registered nurse, a dietitian, an exercise physiologist and a psychologist/counsellor. During the visit, participants will receive a personalized (1) treatment summary, (2) assessment and recommendation on managing physical and psychological symptoms, (3) assessment and recommendation on dietary advice, (4) assessment and recommendation on physical activity, and (5) advice on managing potential psychosocial issues. While this is a multidisciplinary clinic, the nurse will be the core facilitator who will give a summary of health assessment report including personalized healthy lifestyle advice and action plan to each participant at the end of the visit.

Group Type EXPERIMENTAL

Cancer survivorship care intervention

Intervention Type BEHAVIORAL

A one-off face-to-face assessment and personal advice by members of a multidisciplinary team

First stage intervention: Control intervention

Patients randomized to the control group will be given a set of pamphlets explaining symptoms and describing skill-based self-management for symptom management and lifestyle recommendations. Each pamphlet addresses one of the 7 most commonly-reported symptoms (sleep difficulties, fatigue, neuropathy, pain, anxiety, depression, and fear of cancer recurrence) observed in Hong Kong cancer survivors, plus two on lifestyle recommendations (physical activity and healthy diet). All pamphlets are developed based on the self-management framework.

Group Type ACTIVE_COMPARATOR

First stage control intervention

Intervention Type BEHAVIORAL

A set of skill-based pamphlets will be given.

Second stage intervention: Step-up targeted personalized intervention

The step-up targeted personalized intervention will adopt a multi-disciplinary approach but place more emphasis on coaching to enhance patient' skills to manage their symptom burden and weight control.

Group Type EXPERIMENTAL

Step-up targeted personalized intervention

Intervention Type BEHAVIORAL

To provide a more personalized intervention to the participants, but focusing more on symptom management and weight control.

Second stage intervention: Control intervention

Patients randomized to the control arm at the re-assessment at 4-months post-baseline will continue in the trial as usual (i.e. those in the survivorship clinic arm will be asked to follow the advice given by the multidisciplinary team in the initial visit and for those in the control arm will be asked to follow the advices printed in the skill-based self-management pamphlets).

Group Type ACTIVE_COMPARATOR

Second stage control intervention

Intervention Type BEHAVIORAL

Those in the survivorship clinic arm will be asked to follow the advice given by the multidisciplinary team in the initial visit and for those in the control arm will be asked to follow the advices printed in the skill-based self-management pamphlet

Interventions

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Cancer survivorship care intervention

A one-off face-to-face assessment and personal advice by members of a multidisciplinary team

Intervention Type BEHAVIORAL

Step-up targeted personalized intervention

To provide a more personalized intervention to the participants, but focusing more on symptom management and weight control.

Intervention Type BEHAVIORAL

First stage control intervention

A set of skill-based pamphlets will be given.

Intervention Type BEHAVIORAL

Second stage control intervention

Those in the survivorship clinic arm will be asked to follow the advice given by the multidisciplinary team in the initial visit and for those in the control arm will be asked to follow the advices printed in the skill-based self-management pamphlet

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Cantonese- or Mandarin-speaking Chinese patients diagnosed curable cancer
* have completed primary and adjuvant treatment within the past six months

Exclusion Criteria

* Patients diagnosed with metastatic cancer
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Wendy Wing Tak Lam

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wendy Wing Tak Lam, PhD

Role: PRINCIPAL_INVESTIGATOR

School of Public Health, The University of Hong Kong

Locations

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Kwong Wah Hospital-Breast Center

Hong Kong, , Hong Kong

Site Status ACTIVE_NOT_RECRUITING

Pamela Youde Nethersole Eastern Hospital-Department of oncology

Hong Kong, , Hong Kong

Site Status ACTIVE_NOT_RECRUITING

Prince of Wales Hospital-Department of Surgery

Hong Kong, , Hong Kong

Site Status ACTIVE_NOT_RECRUITING

Queen Mary Hospital-Department of Obstetrics & Gynaecology

Hong Kong, , Hong Kong

Site Status RECRUITING

Queen Mary Hospital-Department of Oncology

Hong Kong, , Hong Kong

Site Status RECRUITING

Queen Mary Hospital-Department of Surgery

Hong Kong, , Hong Kong

Site Status RECRUITING

Tung Wah Hospital-Department of Surgery

Hong Kong, , Hong Kong

Site Status ACTIVE_NOT_RECRUITING

Countries

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Hong Kong

Central Contacts

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Wendy Wing Tak Lam, PhD

Role: CONTACT

+852 39179878

Facility Contacts

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Karen Chan

Role: primary

Wendy Chan

Role: primary

Dominic Foo

Role: primary

Other Identifiers

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UW20-100

Identifier Type: -

Identifier Source: org_study_id

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