Accelerating the Implementation of a Breast and Cervical Cancer Screening and HPV Vaccination Intervention

NCT ID: NCT05524480

Last Updated: 2024-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

2000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-02

Study Completion Date

2025-09-30

Brief Summary

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The proposed study will develop and test an implementation strategy called Salud en Mis Manos-Dissemination and Implementation Assistance (SEMM-DIA) which is an internet-accessible cross-platform that includes additional implementation support strategies to increase the reach, effectiveness, and implementation of an evidence-based breast and cervical cancer screening and HPV vaccination program for Latinas (SEMM).

Detailed Description

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This study tests a multicomponent and multifaceted implementation strategy, SEMM-DIA and serves as a model for developing other implementation strategies designed to build the capacity of clinic leadership, intervention champions, and LHWs to plan, manage, and deliver SEMM. Investigators will examine the effect of SEMM-DIA program implementation in a randomized group trial comparing the impact of SEMM-DIA vs. SEMM- Usual Implementation Practice on the reach, effectiveness, implementation, and cost-effectiveness of SEMM in safety-net clinics.

Conditions

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Cancer Prevention

Keywords

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Implementation Intervention Cervical Cancer Breast Cancer HPV Vaccination

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Twenty community health centers (CHCs) will be recruited and randomized to either the SEMM-Dissemination and Implementation Assistance arm or the SEMM-Usual Implementation Practice arm.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Salud en Mis Manos - Dissemination and Implementation Assistance

The multi-component and multi-faceted implementation strategy SEMM-DIA

Group Type EXPERIMENTAL

Salud en Mis Manos - Dissemination and Implementation Assistance

Intervention Type BEHAVIORAL

The experimental arm will utilize the multi-component and multifaceted implementation strategy, SEMM-DIA. This includes elements like 1) A program orientation session (virtual or in-person), 2) Technical Assistance for implementers, such as SEMM Program Manager/ Coordinator and LHWs, 3) SEMM program materials (including LHW Training curriculum, in-reach/ outreach materials, patient tracking forms), and 4) Virtual community support (Project ECHO series).

Salud en Mis Manos - Usual Implementation Practice

The SEMM-Usual Implementation Practice arm includes all existing SEMM program materials.

Group Type ACTIVE_COMPARATOR

Salud en Mis Manos- Usual Implementation Practice

Intervention Type BEHAVIORAL

The control arm will undertake SEMM- Usual Implementation Practice, which includes utilizing all existing SEMM program materials (MOPs, LHW Training Curriculum, etc.) which will be shared with clinic staff in PDF form.

Interventions

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Salud en Mis Manos - Dissemination and Implementation Assistance

The experimental arm will utilize the multi-component and multifaceted implementation strategy, SEMM-DIA. This includes elements like 1) A program orientation session (virtual or in-person), 2) Technical Assistance for implementers, such as SEMM Program Manager/ Coordinator and LHWs, 3) SEMM program materials (including LHW Training curriculum, in-reach/ outreach materials, patient tracking forms), and 4) Virtual community support (Project ECHO series).

Intervention Type BEHAVIORAL

Salud en Mis Manos- Usual Implementation Practice

The control arm will undertake SEMM- Usual Implementation Practice, which includes utilizing all existing SEMM program materials (MOPs, LHW Training Curriculum, etc.) which will be shared with clinic staff in PDF form.

Intervention Type BEHAVIORAL

Other Intervention Names

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SEMM-DIA SEMM

Eligibility Criteria

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Inclusion Criteria

* Clinic or community health center (CHC) with LHWs serving Latina populations.
* Expressed intent to participate in the implementation of SEMM.
* Serve low-income populations with low or no-cost screening and vaccination.
* Provide comprehensive primary health care services.


* Latinas who self-identify as Hispanic/Latina.
* Latinas who have at least one unmet breast or cervical cancer prevention need, following Electronic Clinical Quality Measures.
* (1) Latinas aged 21-64 years who have not had a Pap test in the past 3 years, and (2) Latinas aged 30-64 who have not had a HPV test in the past 5 years (CMS eCQM ID: CMS124v9).
* (3) Latinas aged 51-74 years who have not had a mammogram in the past 2 years (CMS eCQM ID: CMS125v9).
* (4) Latinas aged 18-26 years who have not initiated HPV vaccination.

* Note: Some women will have more than one unmet need (e.g., HPV vaccination and pap test), so they will be included in more than one non-adherent group.

Exclusion Criteria

\- Clinics/Community Health Centers not located in Texas.


\- Latinas with a prior or current cancer diagnosis due to modified cancer screening surveillance guidelines for cancer survivors.
Minimum Eligible Age

18 Years

Maximum Eligible Age

74 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Centers for Disease Control and Prevention

FED

Sponsor Role collaborator

The University of Texas Health Science Center, Houston

OTHER

Sponsor Role lead

Responsible Party

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Lara Savas

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lara Savas, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Maria E Fernandez, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Texas Health Science Center, Houston

Locations

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The University of Texas Health Science Center at Houston

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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HSC-SPH-20-1117

Identifier Type: -

Identifier Source: org_study_id