Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure
NCT ID: NCT05520398
Last Updated: 2024-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
90 participants
OBSERVATIONAL
2021-11-10
2025-12-31
Brief Summary
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To understand the neural mechanisms involved in exposure therapy that support success and clinical improvement in order to improve therapy outcomes for OCD patients.
Detailed Description
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In this study the investigators assess patients pre-therapy and post-therapy evaluating symptom severity (measured by the Y-BOCS) and decision-making (measured by online questionnaires and computer-based behavioural tasks).
To examine how decisions are formed in patients undergoing OCD CBT, how behaviour changes after a non-pharmacological therapy module and how it is associated to the alleviation of OCD symptoms.
The study, which will recruit 90 patients, is based at University College London - Wellcome Centre for Human Neuroimaging. This study is a part of the Cognitive and Neural Networks in Psychiatry (CNNP) study.
Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Eligibility Criteria
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Inclusion Criteria
* Fluent in written and spoken English
* Normal/corrected to normal vision
* Expecting to start OCD therapy
Exclusion Criteria
* Hearing conditions: tinnitus, ear inflammation, hearing sensitivity, hearing loss, requires hearing aids
* Colour blindness
* Severe learning disabilities
18 Years
55 Years
ALL
No
Sponsors
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University College, London
OTHER
Responsible Party
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Principal Investigators
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Tobias Hauser, PhD
Role: PRINCIPAL_INVESTIGATOR
University College, London
Locations
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Max Planck UCL Centre for Computational Psychiatry and Ageing Research
London, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Karen Hoang, MSc
Role: primary
Tricia Seow, PhD
Role: backup
Other Identifiers
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15/0541
Identifier Type: -
Identifier Source: org_study_id