Evaluation of the Safety and Efficacy of REBORN System for Lipolysis Treatment

NCT ID: NCT05507528

Last Updated: 2024-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

107 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-30

Study Completion Date

2023-11-11

Brief Summary

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The Lightfective ReBorn System is intended for non-invasive lipolysis of the flanks in individuals with a Body Mass Index (BMI) of 30 or less. The device is intended to affect the appearance of visible fat bulges in the flanks.

Detailed Description

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Body countering and fat reduction treatment are considered to be one of the most popular aesthetic procedures. The Lightfective' ReBorn LED System provides non-invasive fat reduction treatment.

The primary efficacy objective is to demonstrate fat reduction in the treated area after treatment with the ReBorn LED system.

study population, Healthy subjects who seek for fat reduction treatments in the flanks area.

Each subject will undergo 2 treatment visits (one month apart) and follow-up visits.

Conditions

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LIPOLYSIS

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

open label, prospective, single arm, interventional study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Reborn treatment group

The Lightfective ReBorn System is a Diode Light Emitting Diode (LED) System, Fat reduction treatments with the ReBorn LED System visit - include the treatment procedure

Group Type EXPERIMENTAL

reborn treatment

Intervention Type DEVICE

Fat reduction treatments with the ReBorn LED System visit - include the treatment procedure

Interventions

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reborn treatment

Fat reduction treatments with the ReBorn LED System visit - include the treatment procedure

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Male or female subjects \> 22 years of age.
2. Subject has clearly visible fat on the flanks area.
3. Subject has not experienced weight change exceeding 4.5kg in the preceding month.
4. Subject agrees to maintain their weight (i.e., within 2.25kg) by not making any major changes in their diet or lifestyle during the course of the study.
5. Subject is willing and able to comply with protocol requirements and all study visits
6. Subject has provided a written informed consent

Exclusion Criteria

1. Subject underwent a prior surgical procedure(s) in the area of intended treatment within the past 6 months.
2. Subject underwent a prior invasive fat reduction procedure (e.g., liposuction, abdominoplasty, mesotherapy) in the area of intended treatment within the past year.
3. Subject underwent a prior non-invasive fat reduction procedure in the area of intended treatment within the past 6 months.
4. Subject has a known history of subcutaneous injections into the area of intended treatment (e.g., clexane, insulin) within the past month.
5. Subject has a known history of cryoglobulinemia, cold urticaria, or paroxysmal cold hemoglobinuria.
6. Subject has a known history of Reynaud's disease, or any known condition with a response to cold exposure that limits blood flow to the skin.
7. Subject has a history of bleeding disorder, or is taking any medication that in the investigator's opinion may increase the subject's risk of bruising.
8. Subject body mass index (BMI) exceeds 30. BMI is defined as weight in kg divided by the square of the height in cm.
9. Subject is taking or has taken diet pills or supplements within the past month.
10. Subject has any dermatological conditions or scars in the location of the treatment sites that may interfere with the treatment or evaluation.
11. Subject is pregnant or intending to become pregnant in the next 6 months.
12. Subject is lactating or has been lactating in the past 6 months.
13. Subject is unable or unwilling to comply with the study requirements.
14. Subject is currently enrolled in a clinical study of any other unapproved investigational drug or device.
15. Any other condition or laboratory value that would, in the professional opinion of the investigator, potentially affect the subject's response or the integrity of the data or would pose an unacceptable risk to the subject.
16. Subject is currently taking weight reduction medications (e.g., Saxenda).
17. Subject is currently taking GLP-1 receptor agonist medications (e.g., Victoza).
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Lightfective Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Tennessee Clinical Research Center

Tennessee City, Tennessee, United States

Site Status

Herzelia Medical Center - Tal Nachliely clinic

Kiryat Bialik, , Israel

Site Status

rabin medical center - campus Hasharon

Petah Tikva, , Israel

Site Status

Countries

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United States Israel

Other Identifiers

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RB-LF-01

Identifier Type: -

Identifier Source: org_study_id

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