GlideSheath Slender® Versus Conventional 6 French Arterial Sheath: Impact on the Distal Radial Artery Occlusion (SMART)

NCT ID: NCT05501925

Last Updated: 2023-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

600 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-15

Study Completion Date

2024-02-28

Brief Summary

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Compared with conventional artery sheath (TERUMO, Introducer II ), GlideSheath Slender® has more smaller outer-side diameter. The investigators suspected that use of the GlideSheath Slender® can reduce the incidence of distal radial artery occlusion in cardiovascular intervention via dTRA approach.

Detailed Description

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Distal transradial artery (dTRA) approach has emerged as a new approach in cardiovascular intervention in recent years. Compared to the conventional radial artery (CRA) approach, the dTRA approach dramatically reduced the risk of radial artery occlusion (RAO). In recent years, the incidence of distal radial artery occlusion (dRAO) after dTRA intervention has been reported in the literature, ranged from 0.12% to 5.2%. Outside diameter of artery sheath may affect the incidence of dRAO. Retrospective study reported that an artery/ sheath ratio \> 1.0 was least damaging to the vessel during coronary intervention via dTRA. Compared with conventional artery sheath (TERUMO, Introducer II ), 6 French GlideSheath Slender® has more smaller outer-side diameter (2.46mm vs. 2.62mm). The investigators suspected that use of the GlideSheath Slender can reduce the incidence of dRAO in cardiovascular intervention via dTRA approach.

Conditions

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Coronary Artery Disease Cardiovascular Diseases

Keywords

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distal radial artery distal radial artery occlusion cardiovascular intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

GlideSheath Slender® group Conventional Sheath group (TERUMO, Introducer II )
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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GlideSheath Slender®

Placement of 6 French GlideSheath Slender® for cardiovascular intervention via distal radial artery

Group Type EXPERIMENTAL

GlideSheath Slender® and conventional arterial sheath

Intervention Type DEVICE

Using the GlideSheath Slender® with the outside diameter 2.46mm

Conventional Sheath

Placement of 6 French conventional Sheath (TERUMO, Introducer II ) for cardiovascular intervention via distal radial artery

Group Type ACTIVE_COMPARATOR

Conventional arterial sheath

Intervention Type DEVICE

Placement of 6 French conventional Sheath (TERUMO, Introducer II )

Interventions

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GlideSheath Slender® and conventional arterial sheath

Using the GlideSheath Slender® with the outside diameter 2.46mm

Intervention Type DEVICE

Conventional arterial sheath

Placement of 6 French conventional Sheath (TERUMO, Introducer II )

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Palpable distal radial and conventional radial artery

Exclusion Criteria

* Age ≥ 90years
* Height≥ 185cm
* ST-segment elevation myocardial infarction or Cardiogenic shock
* Contraindications to puncture at the puncture site
* Diameter of DRA less than 1.5mm or RAO
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wujin People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gaojun Cai

Role: STUDY_CHAIR

Wujin hospital affiliated with Jiangsu University

Locations

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Changzhou Wujin People's Hospital

Changzhou, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Gaojun Cai, Dr.

Role: CONTACT

Phone: 086-0519-85579193

Email: [email protected]

Facility Contacts

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Gaojun Cai, MD

Role: primary

References

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Kiemeneij F. Left distal transradial access in the anatomical snuffbox for coronary angiography (ldTRA) and interventions (ldTRI). EuroIntervention. 2017 Sep 20;13(7):851-857. doi: 10.4244/EIJ-D-17-00079.

Reference Type BACKGROUND
PMID: 28506941 (View on PubMed)

Achim A, Kakonyi K, Jambrik Z, Nagy F, Toth J, Sasi V, Hausinger P, Nemes A, Varga A, Bertrand OF, Ruzsa Z. Distal Radial Artery Access for Coronary and Peripheral Procedures: A Multicenter Experience. J Clin Med. 2021 Dec 20;10(24):5974. doi: 10.3390/jcm10245974.

Reference Type BACKGROUND
PMID: 34945269 (View on PubMed)

Tsigkas G, Papageorgiou A, Moulias A, Kalogeropoulos AP, Papageorgopoulou C, Apostolos A, Papanikolaou A, Vasilagkos G, Davlouros P. Distal or Traditional Transradial Access Site for Coronary Procedures: A Single-Center, Randomized Study. JACC Cardiovasc Interv. 2022 Jan 10;15(1):22-32. doi: 10.1016/j.jcin.2021.09.037. Epub 2021 Dec 15.

Reference Type BACKGROUND
PMID: 34922888 (View on PubMed)

Liang C, Han Q, Jia Y, Fan C, Qin G. Distal Transradial Access in Anatomical Snuffbox for Coronary Angiography and Intervention: An Updated Meta-Analysis. J Interv Cardiol. 2021 Jul 22;2021:7099044. doi: 10.1155/2021/7099044. eCollection 2021.

Reference Type BACKGROUND
PMID: 34381321 (View on PubMed)

Cai G, Huang H, Li F, Shi G, Yu X, Yu L. Distal transradial access: a review of the feasibility and safety in cardiovascular angiography and intervention. BMC Cardiovasc Disord. 2020 Aug 5;20(1):356. doi: 10.1186/s12872-020-01625-8.

Reference Type BACKGROUND
PMID: 32758150 (View on PubMed)

Naito T, Sawaoka T, Sasaki K, Iida K, Sakuraba S, Yokohama K, Sato H, Soma M, Okamura E, Harada T, Yoshimachi F. Evaluation of the diameter of the distal radial artery at the anatomical snuff box using ultrasound in Japanese patients. Cardiovasc Interv Ther. 2019 Oct;34(4):312-316. doi: 10.1007/s12928-018-00567-5. Epub 2019 Jan 7.

Reference Type BACKGROUND
PMID: 30617776 (View on PubMed)

Lu W, Chen T, Wang H, Yang A, Li L, Shi G, Xue S, Li F, Xiao J, Gu J, Zhang L, Liang X, Li W, Cai G. Comparison of the Effect of a 6-French Glidesheath Slender and a Conventional Sheath on Distal Radial Artery Occlusion: A Randomized Controlled Trial. Can J Cardiol. 2024 Nov;40(11):2292-2300. doi: 10.1016/j.cjca.2024.07.011. Epub 2024 Jul 19.

Reference Type DERIVED
PMID: 39032557 (View on PubMed)

Other Identifiers

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WJH20220731

Identifier Type: -

Identifier Source: org_study_id