68Ga-FAPI PET/CT for the Detection of Adenoid Cystic Carcinoma(ACC)

NCT ID: NCT05499936

Last Updated: 2022-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-01

Study Completion Date

2022-12-31

Brief Summary

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This study was used to study the diagnostic value of 68Ga-FAPI, a novel fibroblast activating inhibitor, in metastatic adenoid cystic carcinoma(ACC)

Detailed Description

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68Ga-FAPI is a positron labeled inhibitor of fibroblast activating protein, which has been widely used in malignant tumor imaging in recent years. Adenoid cystic carcinoma (ACC) is a rare epithelial malignant tumor, which usually originates from salivary glands. Its typical characteristics are long clinical course and high rate of distant metastasis. The purpose of this study was to investigate the clinical value of 68Ga Fapi pet/ct in metastatic adenoid cystic carcinoma.

Conditions

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68Ga-FAPI PET/CT Metastatic Adenoid Cystic Carcinoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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68Ga-FAPI PET/CT

Imaging was performed 30-60 minutes after injection of 2-4mci 68Ga-FAPI tracer

Group Type EXPERIMENTAL

68Ga-FAPI

Intervention Type DRUG

68Ga-FAPI were injected into the patients before the PET/CT scans

Interventions

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68Ga-FAPI

68Ga-FAPI were injected into the patients before the PET/CT scans

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients with ACC suspected metastatic tumor,and being able to provide basic information and sign the written informed consent form

Exclusion Criteria

* claustrophobia, pregnancy, breastfeeding, kidney or liver failure, inability to fulfill the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zhaohui Zhu

Role: STUDY_CHAIR

Peking Union Medical College Hospital

Locations

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Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Rongxi Wang

Role: CONTACT

+8619800370331

Zhaohui Zhu

Role: CONTACT

Facility Contacts

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Rongxi Wang

Role: primary

Role: backup

+8619800370331

Other Identifiers

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PUMCHFAPI-ACC

Identifier Type: -

Identifier Source: org_study_id

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