Adherence to Guidelines VAccination in Type 1 DIabetes Mellitus Patients (AVADI-2)

NCT ID: NCT05481801

Last Updated: 2023-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2022-12-31

Brief Summary

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Observational study about adherence to guidelines for Covid-19, Influenza, Pneumococcal and Hepatitis B Vaccination in adult patients with type 1 Diabetes mellitus.

Detailed Description

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Cross-sectional analysis about adherence to guidelines for Covid-19, Influenza, Pneumococcal and Hepatitis B Vaccination in adult patients with type 1 Diabetes mellitus.

All clinical variables are gathered from two EMR softwares (Mambrino XXI and Turriano).

Data analysis is conducted using SPSS (Chicago, IL) statistics software. Results are presented as mean ± SD values or percentages. A paired Student's t-test or a Wilcoxon signed-rank test were used for the analysis of differences. Comparisons between proportions were analyzed using a chi-squared test. A P value \< 0.05 was considered statistically significant.

The protocol was approved by the reference Castilla-La Mancha Public Health Institute Ethic Committee. All participants provided written informed consent.

Conditions

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Type 1 Diabetes

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Vaccination adherence

All type 1 diabetes adults patients attended in Ciudad Real General University Hospital willl be checked for Covid-19, Influenza Vaccination status, Pneumococcal Vaccination status and Hepatitis B Virus (HBV) status.

Covid-19 vaccination

Intervention Type BIOLOGICAL

Correct Covid19 vaccination status was considered in the following situation:

Received at least two Covid-19 vaccine doses being the last in the last 6 months.

Influenza vaccination

Intervention Type BIOLOGICAL

Correct influenza vaccination status was considered in the following situation:

\- Received at least one Influenza vaccine dose in the last year.

Pneumococal vaccination

Intervention Type BIOLOGICAL

Correct pneumococal vaccination status was considered if a subject received at least one of the following options:

One pneumococcal conjugate vaccine (PCV) 13 dose in the last year. One PCV13 dose following a pneumococcal polysaccharide vaccine (PPSV) 23 dose between the following 8 weeks and 12 months.

One PPSV 23 dose in the last 5 years. One PPSV23 dose in the last 5 years and a second PPSV23 dose at 5 years or PCV13 at 1 year.

Hepatitis B Virus (HBV) vaccination

Intervention Type BIOLOGICAL

Correct Hepatitis B Virus (HBV) vaccination status was considered in the following situation:

.- Received at least three consecutive doses of HBV vaccine during six consecutive months.

Interventions

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Covid-19 vaccination

Correct Covid19 vaccination status was considered in the following situation:

Received at least two Covid-19 vaccine doses being the last in the last 6 months.

Intervention Type BIOLOGICAL

Influenza vaccination

Correct influenza vaccination status was considered in the following situation:

\- Received at least one Influenza vaccine dose in the last year.

Intervention Type BIOLOGICAL

Pneumococal vaccination

Correct pneumococal vaccination status was considered if a subject received at least one of the following options:

One pneumococcal conjugate vaccine (PCV) 13 dose in the last year. One PCV13 dose following a pneumococcal polysaccharide vaccine (PPSV) 23 dose between the following 8 weeks and 12 months.

One PPSV 23 dose in the last 5 years. One PPSV23 dose in the last 5 years and a second PPSV23 dose at 5 years or PCV13 at 1 year.

Intervention Type BIOLOGICAL

Hepatitis B Virus (HBV) vaccination

Correct Hepatitis B Virus (HBV) vaccination status was considered in the following situation:

.- Received at least three consecutive doses of HBV vaccine during six consecutive months.

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* Type 1 diabetes
* Age: 18 yrs. or older

Exclusion Criteria

* Other diabetes types.
* Younger than 18 years.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Castilla-La Mancha Health Service

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Ciudad Real General University Hospital

Ciudad Real, , Spain

Site Status

Countries

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Spain

References

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Moreno-Fernandez J, Garcia-Seco JA, Rodrigo EMO, Segura AMS, Garcia-Seco F, Munoz-Rodriguez JR. Vaccination adherence to influenza, pneumococcal and hepatitis B virus in adult type 1 diabetes mellitus patients. Prim Care Diabetes. 2020 Aug;14(4):343-348. doi: 10.1016/j.pcd.2019.09.004. Epub 2019 Sep 30.

Reference Type RESULT
PMID: 31582202 (View on PubMed)

Giatraki V, Dimitriou H, Pappas A, Mamoulakis D, Makris G, Galanakis E, Perdikogianni C. Vaccine coverage in children, adolescents and adults with type 1 diabetes and their close contacts in Crete. Hum Vaccin Immunother. 2021 Nov 2;17(11):4291-4298. doi: 10.1080/21645515.2021.1973882. Epub 2021 Oct 6.

Reference Type RESULT
PMID: 34613871 (View on PubMed)

Wang CH, Jones J, Hilliard ME, Tully C, Monaghan M, Marks BE, Hildebrandt T, Streisand R. Correlates and Patterns of COVID-19 Vaccination Intentions among Parents of Children with Type 1 Diabetes. J Pediatr Psychol. 2022 Aug 12;47(8):883-891. doi: 10.1093/jpepsy/jsac048.

Reference Type RESULT
PMID: 35689648 (View on PubMed)

Other Identifiers

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C-549

Identifier Type: -

Identifier Source: org_study_id

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