Effect of High Flow Nasal Cannula Versus Continues Positive Airway Pressure in Adults With Obstructive Sleep Apnea
NCT ID: NCT05475119
Last Updated: 2022-07-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2022-06-01
2022-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Participants diagnosed with Obstructive Sleep Apnea
The participants will sleep three nights at the sleep lab and undergo in their first night, Polysomnography (PSG). Then at random, some of them will do CPAP titration in the second night followed by HFNC titration in the third night. While others will do HFNC titration in the second night followed by CPAP titration in the third night
Continuous Positive Airway Pressure (CPAP)
Continuous Positive Airway Pressure (CPAP) is a form of positive airway pressure ventilation in which a constant level of pressure greater than atmospheric pressure is continuously applied to the upper respiratory tract of an individual.
High Flow Nasal Cannula (HFNC)
High Flow Nasal Cannula (HFNC) is an oxygen supply system capable of delivering up to 100% humidified and heated oxygen at a flow rate of up to 60 liters per minute
Interventions
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Continuous Positive Airway Pressure (CPAP)
Continuous Positive Airway Pressure (CPAP) is a form of positive airway pressure ventilation in which a constant level of pressure greater than atmospheric pressure is continuously applied to the upper respiratory tract of an individual.
High Flow Nasal Cannula (HFNC)
High Flow Nasal Cannula (HFNC) is an oxygen supply system capable of delivering up to 100% humidified and heated oxygen at a flow rate of up to 60 liters per minute
Eligibility Criteria
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Inclusion Criteria
* Diagnosed with Obstructive Sleep Apnea (OSA) based on Polysomnography (PSG) ranging from mild to severe i.e. more than 5
Exclusion Criteria
* Patients with chronic obstructive pulmonary disease
* Patients who have unstable hemodynamic state, who experienced intolerance to HFNC or CPAP
* Patients who are pregnant
* Patients recently underwent surgery
18 Years
ALL
No
Sponsors
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King Abdulaziz University
OTHER
Responsible Party
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Siraj Omar Wali
Director of Sleep Medicine and Research Center, Professor of Medicine
Principal Investigators
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Siraj O Wali, Professor
Role: STUDY_DIRECTOR
Teaching Assistant at King Abdulaziz University
Locations
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King Abdulaziz University Hospital
Jeddah, Western, Saudi Arabia
Countries
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Central Contacts
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Facility Contacts
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References
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Wali S, Batawi G, Bin Afeef G, Bamagoos AA, Jamal A, Kanbr O, Alshumrani R, Alhejaili F, Badr MS. The effectiveness of high-flow nasal cannula therapy in comparison with continuous positive airway pressure therapy in patients with obstructive sleep apnea: an open-label randomized crossover trial. J Clin Sleep Med. 2025 Jun 1;21(6):1023-1031. doi: 10.5664/jcsm.11640.
Other Identifiers
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724-19
Identifier Type: -
Identifier Source: org_study_id
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