Optimizing Cognition Via Exercise and Nutrition

NCT ID: NCT05472831

Last Updated: 2025-08-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 28 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-08-15
• Study Completion Date: 2024-10-19

Brief Summary

Investigators propose to test the preliminary efficacy of the refined BAILAMOS™ Latin dance program plus a culturally tailored MIND diet (Mediterranean-DASH diet intervention for neurodegenerative delay) program on cognitive function among older Latinos (ages 50+) at risk of cognitive decline. This project will test whether participants randomized to the BAILAMOS™ Latin dance plus MIND diet experience better cognitive outcomes than participants randomized to the BAILAMOS™ Latin dance plus a health education program.

Detailed Description

By 2060, the prevalence of Alzheimer's disease (AD) in Latinos is projected to increase by 832%. There is an urgent need to create non-pharmacological interventions to reduce the risk of AD among Latinos. Physical activity (PA) and diet interventions (e.g. Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)) have been shown to decrease the incidence of AD. Behavioral interventions that concomitantly target physical activity (PA) and diet have shown an improvement in cognitive function; however, these studies have not been conducted in older Latinos nor have they included culturally appropriate interventions. The need to test culturally appropriate PA and diet interventions that have the potential to reduce the loss of cognitive function in older Latinos, a group at elevated risk of health disparities, is of high public health importance. OCEAN (Optimizing Cognition via Exercise and Nutrition) is a 6-month multidomain (Latin dance plus MIND DIET) intervention delivered virtually to middle-aged and older Latinos. The investigators propose a pilot randomized controlled trial to test the preliminary efficacy of the refined BAILAMOS™ Latin dance program plus MIND (Mediterranean-DASH diet intervention for neurodegenerative delay)- a new program tailored for the protection of the brain. The impact of the combined program (intervention group (IG)) will be compared to a BAILAMOS™ plus health education (control group (CG)) on cognitive performance among middle-aged to older Latinos at risk of cognitive decline.

Conditions

Cognitive Function 1, Social

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

BAILAMOS dance program plus MIND diet

BAILAMOS dance program plus MIND diet: Includes a 6-month, twice a week x 60 minutes/session, virtually delivered Latin dance program plus a 60 minute MIND diet session per week.

Group Type: EXPERIMENTAL

BAILAMOS dance program plus MIND diet

Intervention Type: BEHAVIORAL

The refined BAILAMOS program is a Latin dance, Spanish-language intervention that encompasses six dance styles (Merengue, Cha Cha Cha, Bachata, Salsa, Cumbia and Samba). The program meets twice weekly for 60 minutes per session during 6-months via Zoom. The experimental group will also receive one, 60 minute MIND diet session per week.

BAILAMOS dance program plus Health Education

BAILAMOS dance program plus Health Education: Includes a 6-month, twice a week x 60 minutes/session, virtually delivered Latin dance program plus a 60 minute health education session per week.

Group Type: EXPERIMENTAL

BAILAMOS dance program plus Health Education

Intervention Type: BEHAVIORAL

The refined BAILAMOS program is a Latin dance, Spanish-language intervention that encompasses six dance styles (Merengue, Cha Cha Cha, Bachata, Salsa, Cumbia and Samba). The program meets twice weekly for 60 minutes per session during 6-months via Zoom. The experimental group will also receive one, 60 minute Health Education session per week.

Interventions

BAILAMOS dance program plus MIND diet

The refined BAILAMOS program is a Latin dance, Spanish-language intervention that encompasses six dance styles (Merengue, Cha Cha Cha, Bachata, Salsa, Cumbia and Samba). The program meets twice weekly for 60 minutes per session during 6-months via Zoom. The experimental group will also receive one, 60 minute MIND diet session per week.

Intervention Type: BEHAVIORAL

BAILAMOS dance program plus Health Education

The refined BAILAMOS program is a Latin dance, Spanish-language intervention that encompasses six dance styles (Merengue, Cha Cha Cha, Bachata, Salsa, Cumbia and Samba). The program meets twice weekly for 60 minutes per session during 6-months via Zoom. The experimental group will also receive one, 60 minute Health Education session per week.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. age 50 years and older

2. self-identification as Latino/Hispanic

3. ability to understand Spanish

4. score of >21 on the Telephone Interview of Cognitive Status (TICs-m)

5. <3 days or <90 minutes of moderate-to-vigorous physical activity per week

6. self-report having a cardiovascular disease (CVD) OR at least one CVD risk factor (i.e., hypertension, hyperlipidemia, diabetes, obesity, current smoker, or family history of CVD) OR family history of Alzheimer's disease

7. administer EASY questionnaire-yes to any question means they will need medical clearance)

8. Suboptimal diet assessment <8

9. must be able to attend a one-hour orientation before the start of the intervention

10. have access to a tablet or computer with internet access.

Exclusion Criteria

1. significant physical illness or medical condition that would preclude participation in a dance program

2. current or past history of a significant psychiatric condition that would interfere with participation in the study

3. presence of self-reported uncontrolled cardiovascular disease or uncontrolled diabetes mellitus

4. severe chronic obstructive pulmonary disease

5. recent healing or unhealed fracture(s)

6. had recurrent falls in the past 12 months

7. hip or knee replacement

8. participated in a structured dance program for 2 or more days in the past month

9. Sub-optimal diet assessment >8

10. Cannot attend a one-hour orientation before the start of the intervention

11. Travel for more than 2-weeks throughout course of intervention and do not have access to internet

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Illinois at Chicago

OTHER

Sponsor Role: collaborator

National Institute on Aging (NIA)

NIH

Sponsor Role: collaborator

University of Illinois at Urbana-Champaign

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Susan Hughes, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Illinois at Chicago

Locations

University of Illinois at Urbana-Champaign

Urbana, Illinois, United States

Countries

United States

Other Identifiers

5P30AG022849-18

Identifier Type: NIH

Identifier Source: secondary_id

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5P30AG022849-18

Identifier Type: NIH

Identifier Source: org_study_id

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