SUCTIONING AT BIRTH WITH BULB SYRINGE OR SUCTION CATHETER: A RANDOMIZED CONTROLLED TRIAL

NCT ID: NCT05472155

Last Updated: 2023-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-07-21

Study Completion Date

2022-10-30

Brief Summary

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This study is designed to compare two different methods of oropharyngeal suctioning (with bulb syringe or suction catheter) in newborn infants at birth.

Detailed Description

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Objective of the study: This trial aims to compare two different methods of oropharyngeal suctioning (with bulb syringe or suction catheter) in newborn infants needing suctioning at birth.

Primary outcome measure: Oxygen saturation during the first 10 minutes of life.

Study design: This is a single center, prospective, randomized clinical trial comparing two different methods of oropharyngeal suctioning (with bulb syringe or suction catheter) in newborn infants needing suctioning at birth.

Setting: The study is conducted at the St. Luke Catholic Hospital in Wolisso (Ethiopia), which is a level III hospital with around 3,600 deliveries per year.

Immediately after birth, all infants needing suctioning are randomized to receive suctioning with bulb syringe or suction catheter. All resuscitative procedures are performed following the Helping Babies Breathe algorithm. An external observer, not involved in the care of the newborn, is responsible of the positioning the probe of the pulse oximeter and the collection of the data.

We aim to enroll 60 neonates.

Conditions

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Neonatal Resuscitation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Masking is not possible due to the study design. Only statistician who will perform the analysis will be blind to the arm allocation.

Study Groups

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Oropharyngeal suctioning with a bulb syringe

Newborn infants who have obvious obstruction to spontaneous breathing or who require positive pressure ventilation immediately after birth will be suctioned with a bulb syringe

Group Type EXPERIMENTAL

Bulb syringe

Intervention Type DEVICE

Suctioning with a bulb syringe

Oropharyngeal suctioning with a suction catheter

Newborn infants who have obvious obstruction to spontaneous breathing or who require positive pressure ventilation immediately after birth will be suctioned with a suction catheter

Group Type ACTIVE_COMPARATOR

Suction catheter

Intervention Type DEVICE

Suctioned with a suction catheter

Interventions

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Bulb syringe

Suctioning with a bulb syringe

Intervention Type DEVICE

Suction catheter

Suctioned with a suction catheter

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* inborn infants (and)
* need for suctioning at birth (and)
* parental consent

Exclusion Criteria

* Major congenital malformations
* Parental refusal to participate in the study
Minimum Eligible Age

1 Minute

Maximum Eligible Age

2 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Doctors with Africa - CUAMM

OTHER

Sponsor Role collaborator

University Hospital Padova

OTHER

Sponsor Role lead

Responsible Party

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Daniele Trevisanuto

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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St. Luke Catholic Hospital, Wolisso, Ethiopia

Addis Ababa, , Ethiopia

Site Status

Countries

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Ethiopia

References

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Patterson J, North K, Dempsey E, Ishoso D, Trevisanuto D, Lee AC, Kamath-Rayne BD; Newborn Brain Society Guidelines and Publications Committee. Optimizing initial neonatal resuscitation to reduce neonatal encephalopathy around the world. Semin Fetal Neonatal Med. 2021 Aug;26(4):101262. doi: 10.1016/j.siny.2021.101262. Epub 2021 Jun 22.

Reference Type RESULT
PMID: 34193380 (View on PubMed)

Foster JP, Dawson JA, Davis PG, Dahlen HG. Routine oro/nasopharyngeal suction versus no suction at birth. Cochrane Database Syst Rev. 2017 Apr 18;4(4):CD010332. doi: 10.1002/14651858.CD010332.pub2.

Reference Type RESULT
PMID: 28419406 (View on PubMed)

Lawn JE, Blencowe H, Oza S, You D, Lee AC, Waiswa P, Lalli M, Bhutta Z, Barros AJ, Christian P, Mathers C, Cousens SN; Lancet Every Newborn Study Group. Every Newborn: progress, priorities, and potential beyond survival. Lancet. 2014 Jul 12;384(9938):189-205. doi: 10.1016/S0140-6736(14)60496-7. Epub 2014 May 19.

Reference Type RESULT
PMID: 24853593 (View on PubMed)

Kamath-Rayne BD, Berkelhamer SK, Kc A, Ersdal HL, Niermeyer S. Neonatal resuscitation in global health settings: an examination of the past to prepare for the future. Pediatr Res. 2017 Aug;82(2):194-200. doi: 10.1038/pr.2017.48. Epub 2017 May 24.

Reference Type RESULT
PMID: 28419084 (View on PubMed)

Related Links

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Other Identifiers

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NEOUNIPD3(2022)

Identifier Type: -

Identifier Source: org_study_id