Pneumocystis Jirovecii Pneumonia in Non-HIV-infected Immunocompromised Patients

NCT ID: NCT05458752

Last Updated: 2023-07-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

133 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-01

Study Completion Date

2023-07-01

Brief Summary

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Pneumocystis jirovecii pneumonia (PjP) is a rare infectiouse disease with a high level of mortality. PjP is a classical opportunistic infection which concern HIV infected and immunocompromised patients. During the past decade, several therapeutic's progresses have been done in oncology, immunology and hematology. As a consequence, patients benefited of greater treatment efficacy but are exposed to a higher risk of opportunistic infections as PjP. The investigators hypothesis is that PjP incidence increase and its form is depending of underlying immune conditions. The investigators aim to describe its incidence, the PjP forms depending on comorbidities and to identifiy pronostics factors.

Detailed Description

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Conditions

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Pneumocystis Jirovecii Infection

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Underlying immune condition at risk of Pneumocystis jirovecii pneumonia excluding HIV infection
* Clinical, biological and radiological presentation which evoke Pneumocystis jirovecii pneumonia
* Microbiological confirmation by respiratory specimen analyses ( specific coloration and/or IFI and/or PRC)

Exclusion Criteria

* No microbiological confirmation by respiratory specimen analyses
* Proved HIV infection
* Patient denied to particpate
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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LEFEVRE Benjamin

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Université de Lorraine, CHRU Nancy and APEMAC

Vandœuvre-lès-Nancy, Lorraine, France

Site Status

Countries

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France

Other Identifiers

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2020PI184-Pre-existing datas

Identifier Type: -

Identifier Source: org_study_id

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